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OTHER APPLICATIONS. However, our mathematical method can also be used not only for mapping and determination of the genomes of viruses and subsequent prediction of their mutations, but also in astrophysical and cosmological systems. Following symmetry in biological nature gives us a chance to also compute the structures of biological systems in our description of the mutation genes.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

BRIDGING QUANTUM AND BIOLOGICAL. “The relevant point of our approach is the fact that quantum field theory developed for physics, in particular, the Chern–Simons theory, is extremely useful for describing biological systems, despite the huge difference in orders of magnitude between fundamental particles and genetic code.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

BIOLOGICAL UTILITY. “The result of the computation of the RSA algorithm for public and private keys in normal and cancer genes appeared to be significant for the biological cryptosystem. Finally, we used the Chern–Simons current to plot the tensor correlation and compute the image of spectra for cancer signature.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

SUMMARY. “In conclusion, we applied a direct application of algebraic topological quantum cryptography and quantum field theory with loop braid group theory directly to perform the analysis of the ALX1 cancer gene for the detection of a cancer signature. We proposed and used a new theory of quantum public key encryption in a cancer cryptosystem.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

WORK TO BE DONE. “In the future, the application of the methodology can be developed into more practical automatic detection of mutated genes, either for medical purposes or for imaging production of the cancer genome project.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

CLINICAL UTILITY. “We hope for the application in cancer genes, but at first the genes on which the measurements can be made must be identified by genetic experts. However, we provide the tool for the terminal measurements incorporated into more complex biophysical experiments.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

THE FILTER. “With our model we are looking for the effective change of topology of proteins, i.e., the stable structures of noncoding DNA binding to genes; this procedure selects only certain structures that can be detected.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

NEW TOOL. “We can train our algorithm on the different versions of the genes, on normal genes with non-modified sequences of nucleotides or on their mutated versions as cancer genes, which code different structures than the normal ones.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

TEMPORAL VIEW. “The incorrect amino acids can be inserted into a protein molecule, the synthesis of a protein can be prematurely terminated, and the mutated codon can code the same amino acid as the non-mutated codon. As a consequence of DNA constant change, the difference between the mutated and normal versions of the gene changes over time.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn

GENE-LEVEL MUTATIONS. “It may be a swapping of one nucleotide for another one, a deleting or omitting of a specific nucleotide from the strand, or an inserting of an extra nucleotide into the replication strand. Besides the single codon substitutions, on the level of codons there exist other categories of mutations.” https://www.mdpi.com/2073-8994/12/8/1214/htm View in LinkedIn