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MANAGEMENT, MANAGEMENT, MANAGEMENT, is a key to startups, as true as location is in real estate transactions. One trait I have observed in several talented Founder-CEOs is a curious loyalty and hesitancy to fire a bad apple even when it is clearly the case. In all instances, after-the-fact relief was experienced, along with the realization it was very long overdue. Act decisively, be fair and consistent, and this includes acknowledging YOU made the bad hire. People will understand. http://lnkd.in/tGUwYJ View in LinkedIn

MEDICAL DEVICES ARE EXPENSIVE TO DEVELOP, so read this summary of ways to avoid big expenses. As usual, the FDA is one of the cost hurdles. http://lnkd.in/zmG-pf View in LinkedIn

WITHOUT FEAR AND HUNGER, FOUNDERS CANNOT ATTEMPT THE IMPOSSIBLE. These are vital ingredients for sharpening and focusing intentionality. Always remember that those working for the 800 lb gorilla (your worst competitor) are comfortable, secure, and not ever going to stretch and attempt the impossible. A big competitor is not as bad as it looks. View in LinkedIn

DNA SEQUENCING FOR 900 USD? We have been talking about this possibility for years. Harvard's George Church is at the heart of another major advance. This GAME CHANGER is going to have enormous consequences. DNA sequences are going to be at the dining room table, under furious debate by ethicists, and at the forefront of disease gene mapping. The Genie is out of the bottle now, and the only question is how we wisely use this knowledge to create healthier societies, and at last enter the practice of PREVENTATIVE MEDICINE. http://lnkd.in/pDSXqm View in LinkedIn

THE EUROPEAN LEAD FACTORY OF SHELVED DRUG CANDIDATES is an historic initiative. Previously bunkered, many of these molecules have been tested for safety in man. They were developed because they were potent biological modifiers. Opening the repurposing door to academia and industry is valuable. This is one of a number of initiatives that Big Pharma is taking to remedy a broken discovery model. Everyone wins. http://pipeline.corante.com/archives/2013/02/12/the_european_lead_factory.php View in LinkedIn

SCREENING DRUGS IN CULTURED PATIENT TISSUES HAS ADVANTAGES, as it is well known that animal trials can be misleading. This article summarizes the case in mouse models of inflammatory disease. http://pipeline.corante.com/archives/2013/02/13/mouse_models_of_inflammation_are_basically_worthless_now_we_know.php View in LinkedIn

LEGAL REFORM IN THE US IS OVERDUE. If the system had the party who lost paying legal fees, and more, frivolous class action suits would be reduced. A country where lawsuits are a gravy train for a few unscrupulous players, is destined to be hamstrung until it is reformed. No other country is so litigious, or cowered by greedy lawyers. http://lnkd.in/NGrvDk View in LinkedIn

THE CHINESE GOVERNMENT INCENTIVES HAVE MADE CHINA A LEADING PATENT FILER. This beautiful Infographic shows the power of incentives in stimulating innovation, as well as the sheer size of the society. Harness the two together, and you create an unstoppable machine. Most interesting of all is that this also signals a new era where China may recognize IP rights and behave more equitably over patent violations. A hopeful sign in one of the world's largest markets. http://ipinsiders.com/m/blogpost?id=2599317%3ABlogPost%3A43638 View in LinkedIn

MAKING IP MORE ACCESSIBLE by methods like rating systems is a worthy cause. IP is a critical driver of investment in innovation. Out of the approximately 7 M patents in the USPTO, I estimate (from experience not empirically) that less than 15% are actually licensed and used to develop products. This is a goldmine for new product ideas, even when you discard the one third that are either impractical or just academic. http://lnkd.in/zGnei8 View in LinkedIn