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HIGHLY CONSERVED. "The ATP synthase enzymes have been remarkably conserved through evolution. The bacterial enzymes are essentially the same in structure and function as those from mitochondria of animals, plants and fungi, and the chloroplasts of plants." https://lnkd.in/eGC7rMN View in LinkedIn

MOLECULAR ANIMATION of ATP synthase. This exquisite molecular complex with many moving parts is one of nature's most important molecular machines, for it makes the energy molecule ATP, without which, life as we know it would not exist. https://lnkd.in/eggSdtN View in LinkedIn

ATP is "continuously recycled in organisms: the human body, which on average contains only 250 grams (8.8 oz) of ATP, turns over its own body weight equivalent in ATP each day." https://lnkd.in/eStagA3 View in LinkedIn

THE CORE MACHINERY. "When a strong opposing torque is imposed, the gamma shaft rotates in the opposite direction and drives the F1-motor to synthesize ATP." https://lnkd.in/eYcwEF7 View in LinkedIn

MOLECULAR CURRENCY. "Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer. Metabolic processes that use ATP as an energy source convert it back into its precursors." https://lnkd.in/eStagA3 View in LinkedIn

THE CORE MACHINERY "is the subcomplex F1-motor (F1-ATPase) and performs the reversible mechanochemical coupling. The isolated F1-motor hydrolyzes ATP, which is accompanied by unidirectional rotation of its central gamma shaft." https://lnkd.in/eYcwEF7 View in LinkedIn

ANOTHER BIO-AWARD. "The synthesis of ATP is undoubtedly the most important phenomenon that occurs in living organisms." A separate series on ATP will follow ATP synthase. https://lnkd.in/eaMvYSf View in LinkedIn

TEXT OF ATP SYNTHASE FUNCTIONALITY. This is a thoroughly granular description of one ATP synthase, with details of the molecular pockets, architecture of the peripheral stalks and their subunits. This gives a detailed picture of the sheer complexity of this molecule. https://lnkd.in/eERctEF View in LinkedIn

1997 NOBEL PRIZE for Chemistry went to Dr John E. Walker (Medical Research Council's Laboratory of Molecular Biology (LMB) at Cambridge); Dr Paul D. Boyer (University of California at Los Angeles); and Dr Jens C. Skou (Aarhus University in Denmark) for their groundbreaking studies of ATP synthase. https://lnkd.in/eAtWnVk View in LinkedIn

9,000 RPM MINI-MOTOR. "During ATP synthesis, the central rotor turns...about 150 times every second. In order to provide energy to sustain our lives, every day, each one of us produces a quantity of ATP by this mechanism that is approximately equal to our body weight." A number of commercial motors operate at 9,000 RPM. https://lnkd.in/eu4ehmH View in LinkedIn