linkedin post 2016-06-17 04:40:47

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NEW VIEWPOINT. "Our appreciation of the DNA transactions that replicate and maintain a stable human genome is changing rapidly due to recent discoveries indicating that eukaryotic cells contain many more DNA polymerases than previously thought.' http://www.sciencedirect.com/science/article/pii/S1535610803000278 View in LinkedIn
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linkedin post 2016-06-17 04:36:20

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POLYMERASE TYPES. "DNA polymerases are enzymes that synthesize DNA. These proteins have an essential role in genome duplication, but they are also critical for protecting the cell against the effects of DNA damage. There are fifteen different DNA polymerases encoded in mammalian genomes, which are specialized for replication, repair or the tolerance of DNA damage. New evidence is emerging for lesion-specific and tissue-specific functions of DNA polymerases." https://lnkd.in/e_FVkkp View in LinkedIn
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linkedin post 2016-06-17 04:16:03

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DNA DAMAGE CHECKPOINTS. "Critical to the operation of DNA repair systems is the ability cells have to delay progress through the cell cycle until repair is complete. The physiological process of monitoring each task in the cell cycle and controlling the overall cycle so that it remains synchronized is called a ‘checkpoint’." http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.271130/full View in LinkedIn
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