linkedin post 2016-09-22 05:14:40

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FIDELITY. "The faithfulness of conservation which this study observed in the CNGs is unprecedented. The most highly conserved ones have a nucleotide substitution rate, across the studied mammals, that is less than half that of protein-coding genes." (CNG = conserved nongenic (non-gene).sequences). https://lnkd.in/eFvUyrd View in LinkedIn
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linkedin post 2016-09-22 05:11:58

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REGULATORY TOLERANCES. "It was already known that there are sequences outside of genes that are well-conserved between the human and mouse genomes. Untranslated regulatory sequences need to be conserved, for example. But regulatory sequences have more error tolerance than genes, not less." https://lnkd.in/eFvUyrd View in LinkedIn
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linkedin post 2016-09-22 05:04:05

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NON-GENE SEQUENCES. "A team of seven geneticists have found something amazing in the genomes of humans and at least twelve other mammals..."conserved non-genic sequences" (CNGs) of unknown function that are better conserved than genes, and twice as abundant." (Non-genic = not genes). https://lnkd.in/eFvUyrd View in LinkedIn
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linkedin post 2016-09-21 04:21:13

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POST-SCRIPT. "However, the possibility of unwanted ecological effects and near-certainty of spread across political borders demand careful assessment of each potential application. We call for thoughtful, inclusive, and well-informed public discussions to explore the responsible use of this currently theoretical technology." (Understatement). https://lnkd.in/ewXxsGD View in LinkedIn
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