linkedin post 2018-10-07 04:58:07

Uncategorized
NEW SURVIVAL TOOLS. "Why are these protein domains present in the EAM of bacteriophage WO? Some phages of obligate intracellular bacteria may have to overcome two major challenges not encountered by the well-studied phages of free-living bacteria." (EAM = eukaryotic association module). https://lnkd.in/dYh3-r4 View in LinkedIn
Read More

linkedin post 2018-10-07 04:59:42

Uncategorized
DEEP TOOLBOX. "EAM protein domains are prime candidates to aid in functions, including cell lysis (latrotoxin-CTD), manipulation of PCD (NACHT and NB-ARC), host ubiquitination (OTU and Ulp1), insecticidal toxicity (ABC toxin) and interaction with host proteins (ankryin repeats and TPRs)." (EAM = eukaryotic association module). https://lnkd.in/dYh3-r4 View in LinkedIn
Read More

linkedin post 2018-10-07 05:01:51

Uncategorized
PHAGE SUCCESS. "Rather than simply act as virulence factors to benefit their bacterial host, their massive proportion of genomic real estate (up to 60% of the prophage genome) implies that they may be necessary to phage biology and likely have a direct impact on phage propagation." https://lnkd.in/dYh3-r4 View in LinkedIn
Read More

linkedin post 2018-10-07 05:06:41

Uncategorized
EXAPTATIONS OF HOST GENES. "We suggest that the possible acquistion and retooling of intact eukaryotic-like domains in phage WO could be viewed as analogous to the commandeering of host genes by eukaryotic viruses. Whether lateral genetic transfers between metazoans and bacteriophages are common in the symbiotic virosphere remains to be determined." https://lnkd.in/dYh3-r4 View in LinkedIn
Read More

linkedin post 2018-10-08 05:08:34

Uncategorized
MODEL OF AUTONOMOUS DEATH. "We formed the hypothesis that originally immortal terrestrial organisms evolve into ones that are programmed for autonomous death. We then conducted simulation experiments in which we examined this hypothesis using an artificial ecosystem that we designed to refer to a terrestrial ecosystem endowed with Artificial Chemistry." https://lnkd.in/dtsPf9E View in LinkedIn
Read More