linkedin post 2016-03-31 04:35:50
RESISTANCE. "Mutations in Retroviral Genes Associated with Drug Resistance." https://lnkd.in/ewhe2gK View in LinkedIn
linkedin post 2016-03-31 04:38:04
UNEXPECTED. "The presence of retrovirus sequences in animal genomes has been recognized since the 1970s, but is readily explained by the fact that these viruses integrate into chromosomal DNA as part of their normal replication cycle. Unexpectedly, however, we identified a large and diverse population of sequences in animal genomes that are derived from non-retroviral viruses." https://lnkd.in/bBjWGE5 View in LinkedIn
linkedin post 2016-04-01 05:06:06
NON-CODING OR JUNK DNA. "Transposons have been called "junk" DNA and "selfish" DNA, "selfish" because their only function seems to make more copies of themselves and "junk" because there is no obvious benefit to their host." https://lnkd.in/eP9MxUZ View in LinkedIn
linkedin post 2016-04-01 05:09:03
SASUMO ONO, at the City of Hope National Medical Center apparently coined the term "junk DNA" in 1972. Despite no support, the term lingered for decades. "The reason is, that "facts don't kill theories, only theories that exceed obsolete dogma can kill old theories." Time to expunge an ugly idea. https://lnkd.in/eWKpGqJ View in LinkedIn
linkedin post 2016-04-01 05:11:45
"JUNK DNA" is a term that has absolutely no respect for the raw ingenuity or the awesome splendor of nature. 'Vestigial' (or in the process of evolving), or 'fossil' (as in an ancient fingerprint), could be conceivable terms when faced with unknown functionality, but nature is not in the habit of creating molecular junk yards with no utility. View in LinkedIn
linkedin post 2016-04-01 05:14:29
SEEKING FUNCTION. "In genetics, the term junk DNA refers to regions of DNA that are noncoding. DNA contains instructions (coding) that are used to create proteins in the cell. However, the amount of DNA contained inside each cell is vast and not all of the genetic sequences present within a DNA molecule actually code for a protein." https://lnkd.in/eZHPYqA View in LinkedIn
linkedin post 2016-04-01 05:17:08
UNKNOWN FUNCTION. "Some of this noncoding DNA is used to produce non-coding RNA components such as transfer RNA, regulatory RNA and ribosomal RNA. However, other DNA regions are not transcribed into proteins, nor are they used to produce RNA molecules and their function is unknown." https://lnkd.in/eZHPYqA View in LinkedIn
linkedin post 2016-04-01 05:19:21
WHOPPING AMOUNTS. "The proportion of coding versus noncoding DNA varies significantly between species. In the human genome for example, almost all (98%) of the DNA is noncoding, while in bacteria, only 2% of the genetic material does not code for anything." https://lnkd.in/eZHPYqA View in LinkedIn
linkedin post 2016-04-01 05:21:16
98% GENETIC JUNK? This is a completely preposterous idea to biochemists, who are used to the intricate, efficient, and multilayered elegance of metabolic pathways and their regulation, with failsafe pathways guarding essential functioning. Just because we do not understand its function, this is not a reason to call the majority of our DNA "junk", and simply reflects a fundamental disrespect for nature from scientists who should know better. View in LinkedIn
linkedin post 2016-04-02 04:42:43
FRAGMENT FROM NATURE this weekend covers the zany world of cellular proteins, from a 24,000 feet perspective. Exquisite simplicity on one level leads to a multiplying complexity on another. The limited number of chemicals that make up genes, and the limited pallet of amino acids have actually produced a large number of proteins, and groups of proteins that work together. View in LinkedIn