Year: 2022

MOLECULAR REPLICATION. "We’ve published a body of work … where we’ve made small molecules that are capable of copying themselves...Just having a small molecule that replicates itself is not … ultimately very complex.’ https://lnkd.in/dDrKtFQ View in LinkedIn

REPLICON MODEL. "Imagine a molecule that likes its own shape: finding a copy of itself, it will fit neatly with its twin, forming for a while a complete entity. If the original molecule is presented with the component parts of itself, it will assemble these into additional replicas. The process will continue as long as the supply of components lasts." https://lnkd.in/dn83zJW View in LinkedIn

REPLICON PROOF. "My colleagues and I... have designed such self-assembling molecules and crafted them in the laboratory... Our organic molecules, although they operate outside of living systems, help to elucidate some of the essential principles of self-replication.'' https://lnkd.in/dn83zJW View in LinkedIn

LIFE ORIGINS. "According to their model, during the night cycles, multiple short polymers bond to longer polymer strands, which act as templates. These longer template strands hold the shorter polymers in close enough proximity to each other that they can ligate to form a longer strand -- a complementary copy of at least part of the template. Over time, the newly synthesized polymers come to dominate, giving rise to an autocatalytic and self-sustaining system of molecules large enough to potentially encode blueprints for life, the model predicts." https://publishing.aip.org/publishing/journal-highlights/origins-life-new-model-may-explain-emergence-self-replication-early View in LinkedIn

Great initiative! https://www.theguardian.com/world/2018/dec/05/luxembourg-to-become-first-country-to-make-all-public-transport-free?CMP=Share_iOSApp_Other View in LinkedIn

HOUSE OF YOUR DREAMS in Spain in small fishing village half way between Barcelona and France. Amazing access to Europe. Fabulous culture, inexpensive living, sunny and temperate. https://www.lucasfox.com/property-for-sale/spain/costa-brava/tamariu-llafranc-palafrugell/house-villa/cbr15519.html#imagegallery-1 View in LinkedIn

MOLECULAR EVOLUTION. "What we have demonstrated for the first time is that even if all you have is template-assisted ligation, you can still bootstrap the system out of primordial soup," https://publishing.aip.org/publishing/journal-highlights/origins-life-new-model-may-explain-emergence-self-replication-early View in LinkedIn

EMERGENT COMBINATIONS. "A single-celled bacterium is alive, but if you separate the macromolecules that combined to create the bacterium, these units are not alive. Based on our knowledge of macromolecules, we would not have been able to predict that they could combine to form a living organism, nor could we have predicted all of the characteristics of the resulting bacterium." https://www.nature.com/scitable/topicpage/biological-complexity-and-integrative-levels-of-organization-468 View in LinkedIn

SELF-REPLICATING MOLECULES. "He mentioned three specific groups of scientists, including his group, that have created self-replicating molecules, and indicated that there are others. I asked him if these were derived from naturally occurring self-replicating molecules, and he said that none of the molecules were derived from naturally occurring molecules." https://lnkd.in/d9-rKhE View in LinkedIn

ROTAXANE. "Scientists in the UK and Malaysia have created a self-assembling rotaxane that can replicate itself. The result may lead to the development of autonomous chemical systems that mimic cellular processes." http://www.rsc.org/chemistryworld/2015/11/self-replicating-assembly-rotaxane-dna-1 View in LinkedIn