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SMOKE AND FIRES. "Government agencies granted more than $1 million (in 1960s dollars) to conduct such experiments, and 247 research reports appeared in print. Clearly, something was going on here; there were enough encouraging results to beckon others to try their hand." https://lnkd.in/esKEPF7 View in LinkedIn

BOX CHEMISTRY. "The exploration of these confined spaces and of the molecules within them continues to open new frontiers." https://www.ncbi.nlm.nih.gov/pubmed/19603810 View in LinkedIn

TREMENDOUS RESEARCH EFFORT. "In fact, by the time the dust had settled roughly 200 independent research teams — many in the upper tiers of science — conducted memory transfer experiments, using dozens of learning paradigms and 23 types of subjects including, in addition to the flatworm and standard lab rat, octopuses, praying mantes, baby chicks, kittens and honey bees." https://lnkd.in/esKEPF7 View in LinkedIn

CHIRALS IN BOXES. "The capsule remains achiral, but the remaining space is chiral, and coencapsulated molecules respond in an amplified way. We probe the various regions of the capsule with guests of different shape. Primary acetylenes, the narrowest of functional groups, can access the tapered ends of the capsule that exclude functions as small as methyl groups." https://www.ncbi.nlm.nih.gov/pubmed/19603810 View in LinkedIn

DISCREDITED. "The alleged fact that no one was ever able to truly replicate the findings. Those who did report positive results, the story goes, were poor scientists who either conducted sloppy experiments that lacked proper controls or simply deceived themselves." https://lnkd.in/esKEPF7 View in LinkedIn

UNEXPECTED BOX VIRTUES. "We also relate how asymmetric spaces can be created inside the capsule by using a chiral guest. In contrast to the situation in dilute solution, where rapid exchange of solute partners and free molecular motion average out the steric and magnetic effects of chirality, the long lifetimes of the encounters in the capsules magnify the effects of an asymmetric environment." https://lnkd.in/dHEf56Q View in LinkedIn

"ACQUIRED MEMORIES that could survive the process of head regeneration were demonstrated by measuring a direct display of a conditioned response or a faster learning rate (‘savings’) among worm fragments generated from head and tail pieces of previously trained planarians." http://jeb.biologists.org/content/216/20/3799 View in LinkedIn

CONFINED REACTIONS. "Molecules isolated from bulk media in spaces barely large enough to accommodate them and a few neighbors show new phenomena: their activities resemble those of molecules inside biochemical structures--pockets of enzymes, interiors of chaperones, or the inner space of the ribosome--rather than conventional behavior in solution." https://www.ncbi.nlm.nih.gov/pubmed/19603810 View in LinkedIn

ADVANTAGES OF BOXES. "It is now clear that the behavior of molecules in dilute solution is really quite different from their behavior in capsules." https://www.ncbi.nlm.nih.gov/pubmed/19603810 View in LinkedIn

MOLECULAR DECISION-MAKING. "The evolution of behavior. Quantum mechanical and thermal fluctuations in single molecules get incorporated into informational polymers that can then display behavioral chemistry. Natural selection operating on these molecules leads to chemical choice, then to heritable decision making, and ultimately to behaviors ascribed to intelligent organisms." http://www.mdpi.com/2075-1729/2/4/313/htm View in LinkedIn