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HEREDITABLE GENETIC FOSSILS. "If members of these active TE families transpose in the germline, they can create novel insertions that are capable of being inherited, thereby generating human-specific polymorphisms." (TE = transposable elements). https://lnkd.in/dUmVr_n View in LinkedIn

FUNCTIONAL GENETIC FOSSILS. "Nevertheless, there remain a few families of actively transposing human TEs; the active families of human TEs include Alu, L1 and SVA elements. All three of these active families of human TEs are retrotransposons that transpose via reverse transcription of an RNA intermediate." (TE = transposable elements). https://mobilednajournal.biomedcentral.com/articles/10.1186/s13100-015-0052-6 View in LinkedIn

FOSSIL GRAVEYARD. "Much of the human genome sequence, anywhere from ~50 to 70 % depending on estimates, is derived from transposable elements (TE). The vast majority of TE-derived sequences in the genome are remnants of ancient insertion events, which are no longer capable of transposition." https://lnkd.in/dUmVr_n View in LinkedIn

GENE RECRUITMENT. "Comparative genomic analysis reveals numerous cases of recruitment of genes with essential functions in cellular life forms, including those that enable evolutionary transitions." https://lnkd.in/d_h9CX2 View in LinkedIn

PUSH TOWARDS COMPLEXITY. "Only increasing organizational complexity, e.g. emergence of multicellular aggregates, can prevent the collapse of the host–parasite system under the pressure of parasites." https://lnkd.in/d_h9CX2 View in LinkedIn

SO ENDS the peek into radically new thinking about the relationship between genes and traits. The overused word wholistic applies here as never before: in an environmental context. No longer genes causing phenotypes due to their mutations and sequences; but rather, the impact of the ecosystem, non-inherited post-translational methylations of DNA, and the word of today, epigenetics, together with genes, cause the phenotype. We are not just governed by genes. View in LinkedIn

NEW PARADIGM. "The differential view of the GP relationship helps to clarify the genetic and environmental effects on phenotypes and their connection." (GP = genotype-phenotype relationship)." https://lnkd.in/d3vzXnd View in LinkedIn

VAST SAMPLE. "Here we explicitly test the long term determinants of TE evolution by comparing 42 nematode genomes that span over 500 million years of diversification, and include numerous transitions between life history states and RNAi pathways." (TE = transposable elements). https://lnkd.in/drMDPh6 View in LinkedIn

CONSEQUENCES OF SURPRISES. "Nowadays, one should not be surprised that a piece of DNA associated with a complex wing color pattern in one Heliconius butterfly species provides similar wings and collective protection from the same predators when introduced into the genome of other butterflies." https://lnkd.in/d3vzXnd View in LinkedIn

PARASITE DISPARITY. "In contrast, life history and genomic characteristics such as mating system, parasitism, GC content, and RNAi pathways, have been suggested to account for the startling disparity of TE loads in different species." (TE = transposable elements). https://lnkd.in/drMDPh6 View in LinkedIn