Category: Uncategorized

DIPLOID PARTHENOGENESIS. "Development to term of chimaeras between diploid parthenogenetic and fertilised embryos. Parthenogenic mouse embryos have the potential for extensive cellular proliferation as well as differentiation into various cell types. But this potential has been realised only when parthenogenetic embryos have been transferred to extrauterine sites, and in spontaneously occurring ovarian teratomas and teratocarcinomas of parthenogenetic origin." https://lnkd.in/gAXZaG6 View in LinkedIn

ALTERNATIVE GAMETES. "Recently, we and others have derived mammalian androgenetic and parthenogenetic haploid embryonic stem cells (ahESCs and phESCs), and showed that ahESCs can replace gametes to produce offspring, which provided alternative resources for reproduction." https://lnkd.in/gCT7Dcz View in LinkedIn

PURE LINE HAPLOID PLANTS. "Lettuce (Lactuca sativa L.), a well-known and popular leafy vegetable, is consumed worldwide. Its haploid form would provide a good basis for producing a pure line of plants (doubled haploids) allowing new varieties to be regenerated." https://lnkd.in/g4mkgn7 View in LinkedIn

ARTIFICIAL HAPLOIDS. "For the artificial production of haploids several methods are known to be useful, such as crosses between distantly related species, pollination with X-rayed pollen, selection of twin seedlings and delayed pollination. However, the tendency to haploid parthenogenesis is controlled by the genetic make-up of a given strain and an application of those methods may be not always successful." https://lnkd.in/gZ6EwgN View in LinkedIn

PLANT ENGINEERING. "Haploidisation is a biotechnological method used to obtain plants with improved traits that are of use to humans." https://lnkd.in/g4mkgn7 View in LinkedIn

CROP HAPLOIDS. "Haploid plants (characterized by gametic number of chromosomes) are both significant and necessary elements in plant improvement programs. They are important in many basic research disciplines, such as biotechnology, genetics, crop evolution and plant breeding. Moreover, haploids are very useful as a base for the production of homozygous plants in that they expedite the breeding process and can lead to an increase in crop yield." https://lnkd.in/g4mkgn7 View in LinkedIn

"GENOME EDITING Using Mammalian Haploid Cells. Haploid cells are useful for studying gene functions because disruption of a single allele can cause loss-of-function phenotypes. Recent success in generating haploid embryonic stem cells (ESCs) in mice, rats, and monkeys provides a new platform for simple genetic manipulation of the mammalian genome. Use of haploid ESCs enhances the genome-editing potential of the CRISPR/Cas system." http://www.mdpi.com/1422-0067/16/10/23604/htm View in LinkedIn

PARTHENOGENIC PLANT EMBRYOS. "Induced Parthenogenesis with an Apomict-Derived Gene. Haploid plants can be recovered from parthenogenetically-derived embryos. This gene has potential utility for haploid induction through parthenogenesis in reduced eggs or apomixis through induction of parthenogenesis in unreduced eggs." https://pag.confex.com/pag/xxiv/webprogram/Paper18705.html View in LinkedIn

“ZEBRA SHARK surprises scientists by giving birth without male.” http://www.cnn.com/2017/01/17/health/zebra-shark-reproduction/index.html View in LinkedIn

PARTHENOGENIC MAMMALIAN EMBRYOS. "Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection. Mammalian haploid embryonic stem cells (haESCs) have been recently generated from parthenogenetic and androgenetic embryos. Both parthenogenetic haESCs (PG-haESCs) and androgenetic haESCs (AG-haESCs) can be used for cell-based reverse and forward genetic screens on a whole-genome scale." https://lnkd.in/gdkjfHz View in LinkedIn