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"GENOME EDITING Using Mammalian Haploid Cells. Haploid cells are useful for studying gene functions because disruption of a single allele can cause loss-of-function phenotypes. Recent success in generating haploid embryonic stem cells (ESCs) in mice, rats, and monkeys provides a new platform for simple genetic manipulation of the mammalian genome. Use of haploid ESCs enhances the genome-editing potential of the CRISPR/Cas system." http://www.mdpi.com/1422-0067/16/10/23604/htm View in LinkedIn

PARTHENOGENIC PLANT EMBRYOS. "Induced Parthenogenesis with an Apomict-Derived Gene. Haploid plants can be recovered from parthenogenetically-derived embryos. This gene has potential utility for haploid induction through parthenogenesis in reduced eggs or apomixis through induction of parthenogenesis in unreduced eggs." https://pag.confex.com/pag/xxiv/webprogram/Paper18705.html View in LinkedIn

“ZEBRA SHARK surprises scientists by giving birth without male.” http://www.cnn.com/2017/01/17/health/zebra-shark-reproduction/index.html View in LinkedIn

PARTHENOGENIC MAMMALIAN EMBRYOS. "Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection. Mammalian haploid embryonic stem cells (haESCs) have been recently generated from parthenogenetic and androgenetic embryos. Both parthenogenetic haESCs (PG-haESCs) and androgenetic haESCs (AG-haESCs) can be used for cell-based reverse and forward genetic screens on a whole-genome scale." https://lnkd.in/gdkjfHz View in LinkedIn

HUMAN HAPLOIDS. "Generation of human haploid embryonic stem cells from parthenogenetic embryos obtained by microsurgical removal of male pronucleus." https://lnkd.in/gxKpzTq View in LinkedIn

HAPLOID HUMAN STEM CELLS. "Here we generated and analysed a collection of human parthenogenetic ES cell lines originating from haploid oocytes, leading to the successful isolation and maintenance of human ES cell lines with a normal haploid karyotype. Haploid human ES cells exhibited typical pluripotent stem cell characteristics, such as self-renewal capacity and a pluripotency-specific molecular signature." (ES = embryonic stem cells). https://lnkd.in/gQeEBUz View in LinkedIn

POSTEMBRYONIC DEVELOPMENT is “the period in the ontogenesis of multicellular animals that follows the period of embryonic development and usually ends with the onset of sexual maturity and, in most animals, the cessation of growth.” https://lnkd.in/g_83yR2 View in LinkedIn

NEW SPECIES. "From the evolutionary point of view, the presence of males and diploid females with normal meiosis in parthenogenetic populations could be significant as they exhibit the potential to re-evolve either a new sexual species of parthenogenetic ancestry or a new parthenogenetic species by contagious parthenogenesis." https://lnkd.in/gnDJkzh View in LinkedIn

“A DEFINING FEATURE of plants is of course their mostly postembryonic development, which displays substantial plasticity with respect to endogenous as well as environmental cues.” https://lnkd.in/gVFjvM2 View in LinkedIn

TRIPLOID REVERSALS. "Lack of genuine bisexual reproduction owing to either asynaptic meiosis in males, or rarity of males with normal meiosis, suggests that diploids are produced in every generation by parthenogenetic females as reversals from triploidy, with their production being enhanced by environmental factor(s) associated with high altitude." https://lnkd.in/gnDJkzh View in LinkedIn