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ESCAPING RESETTING. "There are exceptions, and some genes specifically escape an epigenetic 2n→n ‘meiotic resetting’, leading to transgenerational epigenetic inheritance." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

EPIGENETIC RESETS “ensures proper development, the acquisition of parent-specific imprints, and might allow for mechanisms limiting the maximal number of possible successive mitoses (“Hayflick limit”, reducing tumour development." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

TWO RESETS. "Metazoan development is under the control of many epigenetic changes (cytosine methylation and chromatin marks) that are irreversibly maintained throughout life and must be reset twice each generation (at the n→2n and 2n→n transitions)." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

EPIGENETIC RESETTING. "It has been suggested that a primary function of meiosis is to allow for epigenetic resetting in eukaryotes." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

TRANSITION. "Meiosis and syngamy represent critical transitions between haploid and diploid phases in each generation." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

NO PLANT ARRESTS. "Meiotic arrests in plants are unknown. Plants seem to completely lack strict mechanisms to arrest the meiotic cell division. Contrary to animals and fungi that for example arrest the cell cycle and abort meiosis once double strand breaks are not repaired, plants will progress through meiosis irrespective of such major defects." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

MEIOTIC ARRESTS. "Whereas male meiosis occurs continuously, female meiosis usually stops twice." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

GERMLINE. "In animals, where haploid mitosis is suppressed, syngamy immediately follows meiosis. Furthermore, specific cells are ‘destined’ at an early stage to eventually undergo meiosis (a.k.a germline), whereas this cell fate is determined much later in fungi, plants and some algae." https://lnkd.in/e2tp_G5 View in LinkedIn

SOMATIC CONTROL. "In metazoans, life cycles are mostly determined by the extent of somatic development within each phase rather than by the timing of meiosis, which can be halted or postponed." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn

CELLULAR BOTTLENECK. "In multicellular eukaryotes, where meiosis is tightly associated with reproduction (unlike in many protists), meiosis is also a cellular and genetic bottleneck at the critical transition between the diploid and the haploid phases." https://lnkd.in/e2tp_G5 View in LinkedIn