Category: Uncategorized

PROGRAMMED MOLECULAR SYSTEMS. “Systems undergoing self-organization, i.e., systems capable of spontaneously generating well-defined, organized, and functional supramolecular architectures by self-assembly from their components, thus behaving as programmed systems.” https://lnkd.in/dN969hA View in LinkedIn

CHEMISTRY OF INFORMATION. “Supramolecular chemistry has developed as the chemistry of the entities generated by intermolecular noncovalent interactions. Through the appropriate manipulation of these interactions, it became progressively the chemistry of molecular information, involving the storage of information at the molecular level, in the structural features, and its retrieval, transfer, and processing at the supramolecular level, by interactional algorithms operating through molecular recognition events based on well-defined interaction patterns (hydrogen bonding arrays, sequences of donor and acceptor groups, ion coordination sites, etc.).” https://lnkd.in/dN969hA View in LinkedIn

MOLECULAR INFORMATION. “Supramolecular chemistry has paved the way toward apprehending chemistry as an information science through the implementation of the concept of molecular information with the aim of gaining progressive control over the spatial (structural) and temporal (dynamic) features of matter and over its complexification through self-organization, the drive to life.” https://lnkd.in/dN969hA View in LinkedIn

ROAD TO COMPLEXITY. “Thus emerges the prime question set to science, in particular to chemistry, the science of the structure and transformation of matter: how does matter become complex? What are the steps and the processes that lead from the elementary particle to the thinking organism, the (present!) entity of highest complexity?” https://lnkd.in/dN969hA View in LinkedIn

INCREASING COMPLEXITY. “As the wind of time blows into the sails of space, the unfolding of the universe nurtures the evolution of matter under the pressure of information. From divided to condensed and on to organized, living, and thinking matter, the path is toward an increase in complexity through self-organization.” https://lnkd.in/dN969hA View in LinkedIn

FRAGMENT FROM NATURE this weekend abstracts a fascinating article about how simple chemicals can self-assemble into complex architectures (supramolecular chemistry), using the weak bond information within molecules, and programming a variety of outputs, leading to truly emergent phenomena at higher levels of complexity. It seems that we have greatly underestimated so-called simple inanimate matter. https://lnkd.in/d88ypEi View in LinkedIn

HOLISTIC INVESTIGATIONS. “Fundamentally, the essence of systems biology is the study of interactions between parts of the system using experimental and computational methods.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn

PERTURBATION BIOLOGY. “A common definition of systems biology is the study of a given biological system by (a) the perturbation of a property of that system, (b) the measurement of resulting gene, protein, and pathway responses, (c) the integration of these data, and (d) the ultimate modeling of these data to describe the system as well as its response to perturbation.” Exceptional paper. https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn

SO ENDS this excerpt on the exciting new thinking about supposedly inert chemicals. The concept of chemical evolution, adaptation and selection helps to bridge the gap in our understanding of the emergence of life from simple chemicals. It is clear that we have underestimated supposedly simple matter, simple chemicals. Nothing is quite what it seems to be. View in LinkedIn

CLEAR MESSAGES. “Self-selection with self-recognition occurs when the structural instructions are sufficiently strong, as is the case in the “correct” pairing of strands of different lengths in the assembly of helicates, inorganic double helices.” https://lnkd.in/dN969hA View in LinkedIn