linkedin post 2013-12-14 15:47:10

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AD has become a dangerous venture for drug companies. Part of the reason for past failures is that the patient pool is heterogeneous. Any drug tested in such a pool will have a diluted statistical power. Aricept may be a good drug in a clean pool. The need to have a homogeneous patient pool will be solved by diagnostics. Secondly, florid AD is probably too late to rescue. The brain is simply too compromised. Going earlier to Mild Cognitive Impairment is intuitively more likely to succeed. FDA has opened that door. http://lnkd.in/dg77Em5 View in LinkedIn
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linkedin post 2013-12-18 06:41:15

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ELECTROPERMANENT MAGNETS for auto-assembling materials. "They allow creating controllable permanent magnets where the magnetic effect can be maintained without requiring a continuous supply of electrical energy. For these reasons, electropermanent magnets are essential components of the research studies aiming to build programmable magnets that can give rise to self-building structures."" " http://en.m.wikipedia.org/wiki/Programmable_matter View in LinkedIn
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linkedin post 2013-12-14 15:40:04

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SYNBIO TO CHANGE OUR WORLD. "Synthetic biology looks poised to change the world in which we live in a manner that parallels the transformation brought about by synthetic chemistry a century ago. Within a few decades, products generated by synthetic biology could become a commonplace an element of our everyday lives."" " http://www.humansandnature.org/synthetic-biology--origin--scope--and-ethics-article-50.php View in LinkedIn
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linkedin post 2013-12-18 06:38:34

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SHAPE CHANGING MOLECULES. "An active area of research is in molecules that can change their shape, as well as other properties, in response to external stimuli. These molecules can be used individually or en masse to form new kinds of materials." The applications of such tech to create "smart drugs" are considerable. " " http://en.m.wikipedia.org/wiki/Programmable_matter View in LinkedIn
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linkedin post 2013-12-14 15:36:30

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EXPECT THE UNEXPECTED. "In the coming decades, we are likely to see a revolution in biology akin to the revolution in chemistry that occurred in the latter half of the nineteenth century. The applications of synthetic biology will be highly varied, and progress and innovation is likely to come from unexpected areas. Biological molecules are self-assembling systems that can adapt to change, show robust homeostasis, and can self-repair." Future Synbio material may have some of these properties. " " http://lnkd.in/dqHXeRT View in LinkedIn
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linkedin post 2013-12-17 07:14:52

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NEW FDA WARNING. "The US health regulator has warned that antibacterial chemicals in soaps and body washes may pose health risks. Recent studies indicate an ingredient in such products could scramble hormone levels and boost drug-proof bacteria. The proposal rule does not apply to alcohol-based hand sanitizers and products used in healthcare settings. Certain ingredients in such products - such as triclosan in liquid soaps and triclocarban in bar soaps - may contribute to bacterial resistance to antibiotics, the agency added."" " http://lnkd.in/dvVpHZB View in LinkedIn
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linkedin post 2013-12-14 15:34:15

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PREDICTING FUTURE UTILITY is very difficult. "In the long term, synthetic biology is likely to have as broad and pervasive a role in our society as the products of both the chemical and electronic revolutions." The lessons learned from the unexpected rise of the modern pharma industry from the work of nineteen century synthetic chemists discovering dyes from coal tar products, also apply to Synbio. Equally, nobody guessed that the Human Genome Project would disrupt the medical paradigm. " " http://lnkd.in/dqHXeRT View in LinkedIn
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linkedin post 2013-12-17 06:12:13

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METAMATERIALS. "One example developed by David Smith and then by John Pendry and David Schuri is of a material that can have its index of refraction tuned so that it can have a different index of refraction at different points in the material. If tuned properly this could result in an "invisibility cloak."" " http://en.m.wikipedia.org/wiki/Programmable_matter View in LinkedIn
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