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DAMNED BY FAINT PRAISE. “Perversely, such vaguely positive but non-specific language past in Decadal surveys has been deployed by NASA as a reason ​not​ to fund SETI.​“ https://lnkd.in/djnMhU6 View in LinkedIn

DEAF EARS. “Tarter et al. (2018) catalogs many past recommendations from National Academies reports, NASA strategy documents, and prior Decadal surveys that endorse NASA’s embrace of SETI or the search for technosignatures, including the 1998, 2003, and 2008 Astrobiology Roadmaps, and the 2015 Astrobiology Strategy document.” https://lnkd.in/djnMhU6 View in LinkedIn

MASSIVE IMPACT IN PLANTS. “In plants, circadian rhythmicity is widespread; a transcriptional circadian cycling has been reported in a range of diverse species, including the model plant Arabidopsis thaliana in which the clock has been well characterized. Approximately one-third of the Arabidopsis transcriptome shows circadian oscillations in abundance when in free-run conditions, indicating direct or indirect circadian control.” https://lnkd.in/dyrdvNg View in LinkedIn

OSCILLATOR HIERARCHIES. “The circadian system of mammals is composed of a hierarchy of oscillators that function at the cellular, tissue and systems levels. A common molecular mechanism underlies the cell autonomous circadian oscillator throughout the body, yet this clock system is adapted to different functional contexts.” https://lnkd.in/dBQ96E6 View in LinkedIn

HUMAN LARKS AND OWLS. “Human subjects can be divided into different chronotypes ranging from very early active “larks” to very late active individuals “owls”. These studies have revealed two unexpected, if not shocking aspects of circadian rhythmicity. First, extreme larks and owls hardly overlap with regard to their sleep-wake cycles. Second, the chronotype changes significantly during the lifetime of an individual.” http://www.smw.ch/content/smw-2014-13984/ View in LinkedIn

Crystallography template, View in LinkedIn

IMPACT ON MAN. “Human birth rates follow a robust circadian oscillation. Thus, between 2 a.m. and 6 a.m. about 1.8-fold more babies are born than between 2 p.m. and 6 p.m.” https://lnkd.in/dP8nvcG View in LinkedIn

WHEELS WITHIN WHEELS. “One recurring theme in clock mechanism is coupled transcription-translation feedback loops. To date, the majority of plant transcription factors constituting these loops. The circadian clock is an endogenous timekeeping mechanism that enables organisms not simply to respond as they experience environmental change but, importantly, to anticipate and prepare for coming change. This ability to coordinate with the environment enhances fitness in bacteria, plants, and animals.” https://lnkd.in/dAX4kdh View in LinkedIn

CLOCK REVIEW ARTICLE. “Circadian clocks have evolved to enhance adaptive physiology in the predictable, fluctuating environment caused by the rotation of the planet....major aspects of nutrient homeostasis, including carbon assimilation and mineral uptake, are under circadian control. It is also emerging that there is feedback of nutritional status to the circadian clock to integrate these processes. https://lnkd.in/dUkZXhu View in LinkedIn

LIVING GYROSCOPE. “Interactions between circadian clocks and photosynthesis for the temporal and spatial coordination of metabolism. A number of recent studies have demonstrated that the circadian clock is integrated very closely with photosynthesis and its metabolic products. We describe how this might provide adaptations to optimize plant performance in an environment that varies both predictably upon a daily and seasonal basis, and unpredictably due to the weather.” https://lnkd.in/dwMRFri View in LinkedIn