PROTOTYPE FORMATS. "They have woven complex nanoscale DNA shapes such as boxes with switchable lids, nanoscale alphabetic letters and even world maps." https://lnkd.in/dDwjZMg View in LinkedIn
DNA BASED ROBOTS. "Nature programs its cellular matter partly by the instructions inherited in the DNA of the genome. But by exploiting the same chemical language of the genes ... researchers have been able to make DNA itself a kind of programmable material, designed to assemble into specific shapes and patterns." https://lnkd.in/dDwjZMg View in LinkedIn
SINGLE STRANDED TILES (SST) OF DNA. "SSTs could organize themselves into drug-delivery machines that maintain their structural integrity until they reach specific cell targets, and because they are synthetic, can be made highly biocompatible." https://lnkd.in/d4HaKCM View in LinkedIn
MASSIVE HORIZONTAL GENE TRANSFER. "L-form-like growth and proliferation would have supported massive genetic flux or horizontal gene transfer. We have observed L-forms to undergo spontaneous fusion, potentially generating heterokaryons or chimaeric genomes, under certain conditions." https://lnkd.in/dKmZZzy View in LinkedIn
PARADIGM SHIFT. "Use of DNA nanotechnology to create programmable nanodevices is an important focus at the Wyss Institute, because we believe so strongly in its potential to produce a paradigm-shifting approach to development of new diagnostics and therapeutics." https://lnkd.in/d4HaKCM View in LinkedIn
"CELL WALL-DEFICIENT variants of bacteria that normally possess a wall have been described many times in the literature, since the original report of Klieneberger nearly 80 years ago ... the new L-form cells completely abandon the normally essential cell division machinery used by virtually all extant bacterial cells, and proliferate instead by a mechanism of membrane tubulation or blebbing." https://lnkd.in/dKmZZzy View in LinkedIn
DNA ORIGAMI FOR DRUG DELIVERY. "DNA origami hinged barrel with logic gates for programmable delivery of drugs. The DNA barrel, which acts as a container, is held shut by special DNA latches that can recognize and seek out combinations of cell-surface proteins, including disease markers. When the latches find their targets they reconfigure, causing the two halves of the barrel to swing open and expose its payload." https://lnkd.in/d6RPeMH View in LinkedIn
CELL WALL DRIVERS. "The shapes of bacteria are determined by their cell walls, and with no cell wall, the L-forms have different shapes from their parent cells. For example, the L-forms of rod-shaped bacteria are typically spherical. L-forms also lack the internal cytoskeleton and cell organelles of their parent cells, creating novel morphological units including filaments, vesicles and granules." https://lnkd.in/dTCkxDw View in LinkedIn
DNA PROGRAMMABLE MOLECULES. "To assemble into specific configurations using the same chemical principles that bind the double helix of the genome. In this way, scientists have woven strands of DNA into complex nanoscale shapes: boxes with switchable lids, letters of the alphabet, even tiny world maps." https://lnkd.in/dzmMmjE View in LinkedIn
THE MARSHALL HYPOTHESIS, as we will see, is an interesting conjecture by an unqualified person that has gone beyond an interesting conjecture to become an unsubstantiated medical protocol. Left as simply a conjecture, it remains provocative, and denies Koch's famous postulates. View in LinkedIn