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SECOND GLANCE. "However, the bacterial proteins with the greatest amino acid similarity to mammalian serine racemase are not racemases at all but rather serine/threonine dehydratases, which also use B6." https://lnkd.in/etGHsGm View in LinkedIn

"AT FIRST GLANCE it might seem that the serine racemase of mammals has evolved from the alanine racemase of prokaryotes, because the two enzymes use the same cofactor to catalyse closely related reactions." https://lnkd.in/etGHsGm View in LinkedIn

D-AMINO ACID CELL WALLS. "Prokaryotic genomes contain a variety of amino acid racemases which produce d-amino acid substrates for incorporation into the cell wall peptidoglycan via the action of d-amino acid transaminase, an enzyme found only in bacteria." https://lnkd.in/etGHsGm View in LinkedIn

ANCIENT ORIGINS. "The concept of treating fecal diseases with fecal matter originated in China millennia ago. Fourth century Chinese medical literature mentions it to treat food poisoning and severe diarrhea." https://lnkd.in/e4DWYcp View in LinkedIn

NMDA RECEPTOR in the mammalian brain is susceptible to cytotoxicity and is involved in seizures, pain and various neurological disorders, via glutamate, and as such is a major drug target. It is key to memory and learning among other important functions. https://lnkd.in/edHFErG View in LinkedIn

POO THERAPY. "The practice of transfaunation has been used for centuries to treat ruminants with severe ruminal acidosis and other gastrointestinal disorders and for the treatment of equine diarrhea." https://lnkd.in/erygCxw View in LinkedIn

NEW DISCOVERY. "The high correlation between d-serine levels and NMDA receptor binding in brain suggested that d-serine might be an endogenous glycine site agonist. Substantial evidence for this proposal has accumulated since 1993." https://lnkd.in/etGHsGm View in LinkedIn

PROBIOTIC WEIGHT LOSS. Probiotics are associated with weight loss in mice and humans. "Probiotic Bifidobacteria breve inhibited weight gain in mice given a high fat diet in a dose-dependent manner." https://lnkd.in/eknVNSM View in LinkedIn

NEW DISCOVERY. "The surprising discovery that the ‘wrong isomer’ of serine occurs naturally in brain grew out of advances in techniques to assay small quantities of d-amino acid isomers against the high background of l-isomers present in biological samples." https://lnkd.in/etGHsGm View in LinkedIn

FMT: "In the United States, the FDA has regulated human feces as an experimental drug since 2013. It has potential to treat obesity, metabolic syndrome, diabetes, and autoimmune conditions." https://lnkd.in/e4DWYcp View in LinkedIn