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NEW DISCOVERY. "The high correlation between d-serine levels and NMDA receptor binding in brain suggested that d-serine might be an endogenous glycine site agonist. Substantial evidence for this proposal has accumulated since 1993." https://lnkd.in/etGHsGm View in LinkedIn

PROBIOTIC WEIGHT LOSS. Probiotics are associated with weight loss in mice and humans. "Probiotic Bifidobacteria breve inhibited weight gain in mice given a high fat diet in a dose-dependent manner." https://lnkd.in/eknVNSM View in LinkedIn

NEW DISCOVERY. "The surprising discovery that the ‘wrong isomer’ of serine occurs naturally in brain grew out of advances in techniques to assay small quantities of d-amino acid isomers against the high background of l-isomers present in biological samples." https://lnkd.in/etGHsGm View in LinkedIn

FMT: "In the United States, the FDA has regulated human feces as an experimental drug since 2013. It has potential to treat obesity, metabolic syndrome, diabetes, and autoimmune conditions." https://lnkd.in/e4DWYcp View in LinkedIn

"PROCESSED FOODS as well as foods resulting from microbial fermentations (yogurt, cheese and other dairy products) contain significant amounts of D-amino acids. D-serine is also present in the mammalian brain where it appears to be produced by an L-serine racemase." https://lnkd.in/eMbE2Rk View in LinkedIn

"FMT has been used experimentally to treat clostridium difficile infection...colitis, constipation, irritable bowel syndrome, and neurological conditions such as multiple sclerosis and Parkinson's." https://lnkd.in/e4DWYcp View in LinkedIn

FECAL BIOTHERAPY. "A fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transplantation of fecal bacteria from a healthy individual into a recipient. FMT involves restoration of the colonic microflora by introducing healthy bacterial flora." https://lnkd.in/e4DWYcp View in LinkedIn

OBESITY BIOME NOT DIVERSE. "The gut microbiota of obese humans are less diverse than their lean twins, consistent with the hypothesis that lower diversity may affect eating behavior and satiety." https://lnkd.in/eknVNSM View in LinkedIn

FRAGMENT IN NATURE this weekend is focused on a radical new opportunity in medicine that has the potential to rock the boat. Fecal transplants to restore unbalanced gut microbiota are being performed worldwide in an experimental basis. This fits with personalized medicine, and with the trend towards cellular therapies (stem cells, phage therapy). It is a (revived) outcome of the Human Microbiome Project. View in LinkedIn

D-ENZYMES. "When Sir Hans Krebs accidentally discovered an enzyme from kidney that recognized ‘non-natural’ D-amino acids (but not their L-counterparts), it was not clear why nature would have created such an enzyme." https://lnkd.in/etGHsGm View in LinkedIn