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REPEAT MOLECULAR MOTIF. "TRPA1 is named for the numerous ankyrin repeats (ARs) on its notably long N-terminus (∼720 amino acids). ARs are 33-amino-acid-long motifs that are generally involved in protein-protein interactions and targeting to the plasma membrane." https://lnkd.in/e-WBvC9 View in LinkedIn

"LASERS are the heart of modern communication technology. As the industry strives continuously to improve the speed, efficiency and compactness of communication equipment, it is constantly on the look-out for new materials, techniques and methods that help the cause. Photonic crystal lasers have caught the attention of scientists and engineers for that very reason." https://lnkd.in/e3AXuz6 View in LinkedIn

INTERFACE WITH OUTSIDE WORLD. "TRPA1 is highly expressed in several neural tissues and is activated by many pungent or irritant compounds, eg, chemicals with alkaline pHs, which can induce acute pain, hyperalgesia, and neurogenic inflammation." https://lnkd.in/eTXyYPf View in LinkedIn

WAVE-GUIDING. "Hyperbolic metamaterials are a multi-functional platform to realize waveguiding, imaging, sensing, quantum and thermal engineering beyond conventional devices. This metamaterial uses the concept of engineering the basic dispersion relation of waves to provide unique electromagnetic modes that can have a broad range of applications." https://lnkd.in/ePrzn3K View in LinkedIn

SUPERFAMILY OF ION CHANNELS. "Transient receptor potential (TRP) channels are polymodal receptors that mediate sensory transduction and are activated by a host of stimuli. The TRP superfamily includes 28 genes that are subdivided into seven subfamilies." https://lnkd.in/eTXyYPf View in LinkedIn

HYPERBOLIC METAMATERIALS "research has captured the imagination of optical engineers and materials scientists because of their varied applications including imaging, cloaking, sensing, waveguiding, and simulating space-time phenomena." https://lnkd.in/ePrzn3K View in LinkedIn

TEASING MECHANISM APART. "The functional differences of thermoTRP channels among species have been utilized for understanding the molecular basis for their activation (or inhibition) mechanisms, and amino acid residues (or domains) responsible for the respective channel properties have been identified in various thermoTRP channels." https://lnkd.in/erbAj5A View in LinkedIn

TRPA1, A BEAUTIFUL MOLECULE. https://lnkd.in/evAgKPd View in LinkedIn

FRAGMENT IN NATURE continues from last weekend with the molecule called TRPA1. A great deal is known about its structure, function and mechanism, and it is an exemplar of the enormous creativity in nature, using a single molecular motif to achieve a phenomenal range of biological functions, many of which are key for survival. View in LinkedIn

"PERIODIC STRUCTURES can block sound waves in certain frequency ranges and directions when interference effects lead to the formation of phononic band gaps. Phononic crystals with diamond symmetry, like this artificial 3D structure, have the largest band gaps." https://lnkd.in/ehwDYhR View in LinkedIn