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THE CORE MACHINERY "is the subcomplex F1-motor (F1-ATPase) and performs the reversible mechanochemical coupling. The isolated F1-motor hydrolyzes ATP, which is accompanied by unidirectional rotation of its central gamma shaft." https://lnkd.in/eYcwEF7 View in LinkedIn

ANOTHER BIO-AWARD. "The synthesis of ATP is undoubtedly the most important phenomenon that occurs in living organisms." A separate series on ATP will follow ATP synthase. https://lnkd.in/eaMvYSf View in LinkedIn

TEXT OF ATP SYNTHASE FUNCTIONALITY. This is a thoroughly granular description of one ATP synthase, with details of the molecular pockets, architecture of the peripheral stalks and their subunits. This gives a detailed picture of the sheer complexity of this molecule. https://lnkd.in/eERctEF View in LinkedIn

1997 NOBEL PRIZE for Chemistry went to Dr John E. Walker (Medical Research Council's Laboratory of Molecular Biology (LMB) at Cambridge); Dr Paul D. Boyer (University of California at Los Angeles); and Dr Jens C. Skou (Aarhus University in Denmark) for their groundbreaking studies of ATP synthase. https://lnkd.in/eAtWnVk View in LinkedIn

9,000 RPM MINI-MOTOR. "During ATP synthesis, the central rotor turns...about 150 times every second. In order to provide energy to sustain our lives, every day, each one of us produces a quantity of ATP by this mechanism that is approximately equal to our body weight." A number of commercial motors operate at 9,000 RPM. https://lnkd.in/eu4ehmH View in LinkedIn

ATP SYNTHASE, which makes the all-important ATP, has been called the "molecular engine of life" as well as paradoxically being "an efficient death machine." This molecule ranks along with DNA, chlorophyll, and a number of other molecules, as one the heavyweight champions of life on planet earth. https://lnkd.in/eNs9_jp View in LinkedIn

TWO MOTORS AND A ROTOR. "One motor generates rotation by consuming energy derived from oxidative metabolism or photosynthesis; the other uses energy transmitted by the rotor to put ATP molecules together from their building blocks, ADP and phosphate." https://lnkd.in/eahb8Gv View in LinkedIn

TWO MOTORS AND A ROTOR. "ATP, the fuel of life, is produced in living cells by a complex molecular machine consisting of two motors linked by a rotor." https://lnkd.in/eahb8Gv View in LinkedIn

CARTOON OF ATP SYNTHASE FUNCTIONALITY. This animation cleverly depicts what entire articles are hard pressed to express, namely, the finely-tuned and intricate function of the proton gradient in the enzyme, and how precisely the entire process operates while spinning at 9,000 RPM. https://lnkd.in/efhjzCY View in LinkedIn

THE ONLY UNIVERSAL NANOMOTOR. "Biological motors are molecular machines found in living systems. Among all known biological nanomotors, ATP synthase stands alone for being the universal nanomotor found in all living systems from bacteria to man." https://lnkd.in/eTYm4q6 View in LinkedIn