Category: Uncategorized

ANNE RICE'S VAMPIRE CHARACTERS LAMENT THE ENNUI OF ETERNAL LIFE, in her playful but serious books. The characters yearn a finite life. It is fascinating to see the sheer number of postings today on the preliminary hypothalamus findings. Remember the autumn leaf? It is easier to discard accumulated broken systems and build from new than to repair. We have increased our longevity in a few generations, but these aspirations being voiced are simply fantasy. http://lnkd.in/zRrRe3 View in LinkedIn

THE FIRST REVERSAL OF MOUSE EPILEPSY WITH MOUSE OR HUMAN STEM CELL TRANSPLANTS. Using mouse cells these researchers eliminated the seizures in half of the mice and significantly reduced the seizures in the other half. While at least five years away from human applications this is big news and may well apply to pain and Parkinson's Disease in the future. A lovely example of macro damage repair using cellular therapies. View in LinkedIn

SYSTEMS BIOLOGY IS THE PATH TO UNLOCK GENE PROMOTERS AND MUCH MORE. View in LinkedIn

THE INNOVATION NETWORK CORPORATION OF JAPAN (INCJ) IS THE LARGEST VC FUND IN THE WORLD AT 22 BN USD. It was formed half of public and half of private funds. I met with Kazuhiro Umeda, an old friend, who is the VP of Life Sciences. He had led a stellar career with JAIC VC in Tokyo, Palo Alto, and as President of the Singapore division. His mission is to innovate the Japanese Healthcare sector. Constantly working, he has a large network to draw from, and a very large budget to make that happen. This very bold initiative must have an impact and help Japan to the Tipping Point for a new economy. View in LinkedIn

THERE ARE NEW ENTREPRENEUR PHILANTHROPIST HEROES. I had dinner with Dr. Nagata MD, PhD, FFPM, Chairman of SNBL Japan, a large CRO founded by his father. He started an innovative nasal drug delivery division within his 3,000 person company, and after almost a decade of failures, cracked nasal dry powder delivery. Not only a Professor, founder of a cancer care facility, he is a Buddhist Monk focused on helping humanity. He will all leave his wealth to charity. These are the fantastic new role models for young entrepreneurs. View in LinkedIn

OH PLEASE! THE URBAN MYTH OF THE COSTS TO DEVELOP A NEW DRUG perpetuates itself dishonestly. It only costs 1 Bn in bloated inefficient Big Pharma with huge carrying costs. But even this number is padded. Do they pay these sums for in-licensed drugs? Rarely. Usually these licenses are hundreds of millions, which pays back the investors in the licensee company very handsomely. You cannot talk out of both sides of the mouth and retain credibility, except with gullible reporters! Let's keep the dialogue honest!! View in LinkedIn

BUST THE URBAN MYTH THAT ALL DRUG DEVELOPMENT COSTS OVER 1Bn USD. These articles continue, sadly. The VC specialty pharma investments, hundreds, would mot exist if this were true. Again: Big Pharma costs for developing a new drug are staggering because of staggering inneficiencies, which do not exist in small companies. View in LinkedIn

A FRESH LOOK AT DATA SUGGESTS BIO RETURNS ARE EARLIER THAN THOUGHT. This shows that some strongly held VC views are prejudices without a factual basis. Great work collecting the data! Make this break the urban myth! http://lnkd.in/wVEBEz View in LinkedIn

NANO TNF ALPHA FOR CANCER ENTERS PHASE II. BETTER TARGETING, LESS TOXICITY. View in LinkedIn

NANOPARTICLE PAYLOAD MODELING. View in LinkedIn