linkedin post 2016-09-20 06:14:25

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"WOLBACHIA are common intracellular bacteria that are found in arthropods and nematodes. These alphaproteobacteria endosymbionts are transmitted vertically through host eggs and alter host biology in diverse ways. Within arthropods, Wolbachia is a reproductive parasite, manipulating the reproductive biology of hosts to increase its own transmission. Although usually vertically inherited, Wolbachia can also move horizontally across species boundaries, resulting in a widespread and global distribution in diverse invertebrate hosts." https://lnkd.in/ekadN4H View in LinkedIn
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linkedin post 2016-09-22 05:14:40

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FIDELITY. "The faithfulness of conservation which this study observed in the CNGs is unprecedented. The most highly conserved ones have a nucleotide substitution rate, across the studied mammals, that is less than half that of protein-coding genes." (CNG = conserved nongenic (non-gene).sequences). https://lnkd.in/eFvUyrd View in LinkedIn
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linkedin post 2016-09-22 05:11:58

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REGULATORY TOLERANCES. "It was already known that there are sequences outside of genes that are well-conserved between the human and mouse genomes. Untranslated regulatory sequences need to be conserved, for example. But regulatory sequences have more error tolerance than genes, not less." https://lnkd.in/eFvUyrd View in LinkedIn
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linkedin post 2016-09-23 04:13:28

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BROAD ONION TEST. "Importantly, the comparison is not restricted to onions versus humans. It could as easily be between pufferfish and lungfish, which differ by ∼350-fold, or members of the genus Allium, which have more than a 4-fold range in genome size that is not the result of polyploidy." http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn
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