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PREFERRED GENOME. "A second intriguing aspect of the diploidization process is that it may be nonrandom with respect to retention of the ancestral progenitor genomes. Phrased alternatively, it has been suggested that one of the two genomes is preferentially retained, often with higher gene expression levels than in the more fractionated genome." http://www.amjbot.org/content/early/2015/10/09/ajb.1500320 View in LinkedIn

HYPOTHESES FOR SELECTIVITY. "A number of nonmutually exclusive explanations have been forwarded to account for these patterns, including differences in the propensity of genes to experience neutral or selectively imposed subfunctionalization or neofunctionalization, constraints imposed by dosage considerations, and the need for stoichiometric balance in multiprotein complexes." http://www.amjbot.org/content/early/2015/10/09/ajb.1500320 View in LinkedIn

SO ENDS a peek at the work of a remarkable scientist who changed biology. This moment in the history of life science was rekindled by a similar firestorm in 2010 when Craig Venter claimed he had created a new branch to the tree of life, Synthia. The reaction of the public and of fellow scientists was equally split between superlative praise and a deluge of denunciation. https://lnkd.in/eQz5W6N View in LinkedIn

NOBEL CANDIDATE. "In 1901 Loeb was a finalist for the first Nobel Prize in Physiology or Medicine." View in LinkedIn

ABIOGENESIS. "But we see that plants and animals during their growth continually transform dead into living matter, and that the chemical processes in living matter do not differ in principle from those in dead matter. There is, therefore, no reason to predict that abiogenesis is impossible, and I believe that it can only help science if the younger investigators realize that experimental abiogenesis is the goal of biology.” (Contrary to the maxim: "only life begets life"). https://lnkd.in/exkuKab View in LinkedIn

NEW BRANCH TO TREE OF LIFE. "It opened up a variety of manipulative possibilities—of controlling sex and "creating wholly new organic forms by varying slightly the conditions of development." https://lnkd.in/eQf5Evv View in LinkedIn

IMMENSE DISCOVERY. "E. G. Conklin (now at the University of Pennsylvania), in announcing Herbst's private letter confirming Loeb's work, considered artificial parthenogenesis "one of the greatest discoveries in biology." https://lnkd.in/eQf5Evv View in LinkedIn

BREAKING SPECIES BARRIERS. "The ability to overcome the triploid block can be asymmetric, with offspring viability dependent on whether the maternal or paternal parent had the higher ploidy level." https://lnkd.in/es_dhAz View in LinkedIn

HAUNTING IMAGE. "While most of the more serious journalists pulled back from the idea that Loeb was "manufacturing" life through artificial parthenogenesis, the image of Loeb as Faust or Frankenstein continued through the rest of the decade." https://lnkd.in/eQf5Evv View in LinkedIn

TABOO LINE. "The term “triploid block” has been coined to describe the regular observation that interploidy crosses, specifically between diploids and tetraploids, often result in early hybrid inviability and sterility." https://lnkd.in/es_dhAz View in LinkedIn