NEW DRUG COSTS for R&D since about 2000 by US Pharma companies sum to approximately 650 Billion USD, or 50-70 Bn USD annually. In addition, there has been less bang for the buck, as efficacy rates have slid south towards placebo. In contrast, VCs spend about 8-10 Bn USD annually on all sectors, with Biopharma being a part of that pie. Thus, for the ~900 new drugs (not NCEs) over that time period, the well over 7X annual spend by Big Pharma can be seen as squandered capital. It is a fortunate thing that most Big Pharma are experimenting with outsourcing/licensing their pipeline stuffers.
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