DOUBLE EVOLUTION. “A single protein sequence can be the basis for many prion strains/variants, with different biological properties based on different amyloid conformations, each rather stably propagating. Prions are unique in that evolution and selection work at both the level of the chromosomal gene encoding the protein, and on the prion itself selecting prion variants.”
https://lnkd.in/eyBEuC7
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022