KEY IN EPIGENETICS. “Thousands of lncRNAs have emerged as key molecular players in epigenetic processes through their association with chromatin modifiers. Specifically, antisense RNAs in the nucleus can act as regulators of their counterpart sense mRNA by modulating chromatin structure in cis and by bridging epigenetic effectors and regulatory complexes at specific genomic loci.”
http://www.mdpi.com/1422-0067/16/2/3251/htm