PROBABILITY MARKERS. “We currently lack the capability to evaluate the impact of most sequence variants found and what their functional consequences are. A decade of Genome-Wide Association Studies have revealed a multitude of common variants associated with various traits and diseases, each of which seems to contribute to or at least to increase the probability of a phenotype by a small amount.”
https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1