MOUSE MODEL. “Ames dwarf (Prop1df/df) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice.”
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072255