linkedin post 2018-08-29 04:31:51

CANDIDATE GENES EMERGE. “In the largest linkage scan thus far performed for human familial longevity, we confirm that the APOE locus is a longevity gene and that additional longevity loci may be identified at 14q11.2, 17q12-q22, and 19p13.3-p13.11. As the latter linkage results are not explained by common variants, we suggest that rare variants play an important role in human familial longevity.” (APOE is a class of fat metabolizing pathway proteins linked to Alzheimer’s).

http://onlinelibrary.wiley.com/doi/10.1111/acel.12039/full

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