INTRINSICALLY DISORDERED (ID) REGIONS. “Proteins containing ID regions tend to take a central role in protein interaction networks; specifically, they act as hubs, interacting with multiple different partners across time and space, allowing for the co-ordination of many cellular activities. Especially critical in determining this role is their ability to bind more than one partner using the same region.”
http://www.biochemj.org/content/454/3/361?sa=X&ved=0CDkQ9QEwEWoVChMIzdjAo5n2xgIVovRyCh0HSAum
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022