Month: September 2022

OTHER CASES. "Limb regeneration can also be observed in insects." https://muse.jhu.edu/article/53800/summary View in LinkedIn

ORIGIN OF REGENERATION. "The first question that arises is whether regenerative ability that is unique to a specific group of animals evolved along a particular phylogenetic path or whether regenerative ability was lost in many groups, including humans, and retained in others. In other words, is regenerative ability the result of a gain of function in some groups or the loss of function in other groups."" " https://lnkd.in/d_NDPcr View in LinkedIn

COMPLEXITY DIMINISHES REGENERATION. "A cursory look at regenerative ability across phylogenetic groups leads to the conclusion that regenerative potential declines with the evolution of complexity. Thus, simple organisms like Hydra and planaria have tremendous regenerative capabilities, whereas vertebrates tend to regenerate poorly." http://onlinelibrary.wiley.com/doi/10.1002/ar.b.20082/full View in LinkedIn

LOSS OF FUNCTION WITH COMPLEXITY. "This suggests that the absence of regenerative ability in mammals is a loss of function, perhaps a consequence of physiological adaptations important for survival following injury." https://lnkd.in/d_NDPcr View in LinkedIn

RESIDUAL ABILITIES. "The observation that fingertips of children have regenerative capacity indicates that the ability for a modest level of regeneration was retained in a context-specific format even in higher mammals." http://onlinelibrary.wiley.com/doi/10.1002/ar.b.20082/full View in LinkedIn

OVERLAPPING GENE SETS. "Not only can developing and regenerating cells interact with one another to build a limb, there are numerous examples of genes whose expression during development and regeneration are identical and other genes whose expression is largely similar." https://lnkd.in/d_NDPcr View in LinkedIn

REGENERATION AND DEVELOPMENT. "Another aspect of regeneration biology that supports this general conclusion is the observation that regenerative potential is enhanced in developing systems, and that the process of limb regeneration, where it occurs, is mechanistically very similar to the process of limb development." https://lnkd.in/d_NDPcr View in LinkedIn

DEVELOPMENT AND DEDIFFERENTIATION. "In other words, there are component parts of the regeneration process that can be considered redevelopment." And can be considered overlapping with dedifferentiation, and similar to aspects of wound healing. https://lnkd.in/d_NDPcr View in LinkedIn

CELLULAR COOPERATION. "Developing and regenerating cells interact with one another to build a limb." http://onlinelibrary.wiley.com/doi/10.1002/ar.b.20082/full View in LinkedIn

SIMILAR GENE SETS. "There are numerous examples of genes whose expression during development and regeneration are identical and other genes whose expression is largely similar." http://onlinelibrary.wiley.com/doi/10.1002/ar.b.20082/full View in LinkedIn