Month: September 2022

MILIEU INTÉRIEUR. "Ample evidence shows that microbes act directly as agents of postembryonic development. For example, fucosyltransferases decorate the surface of the embryonic mammalian intestine with fucose residues that provide a nutrient source for gut microbes, including B. thetaiotaomicron, as they colonize the newborn." http://www.pnas.org/content/110/9/3229.full View in LinkedIn

SQUID EMBRYOGENESIS. "In the squid-vibrio system, a complex organ forms during embryogenesis that facilitates subsequent colonization by the symbiotic bacterium Vibrio fischeri." http://www.pnas.org/content/110/9/3229.full View in LinkedIn

SHARED PRODUCTS. "The products of horizontally acquired microbes can be essential for a range of developmental functions, including influences on larval growth rate and body size in invertebrates, postembryonic maturation and renewal of epithelia in invertebrates and vertebrates, development and specification of the gut-associated lymphoid tissues in vertebrates, activation of the immune system in tsetse flies, and normal brain development in mammals." http://www.pnas.org/content/110/9/3229.full View in LinkedIn

LIFE CYCLE TRIGGERS. "Perhaps the most pervasive example of microbial signaling in animal development is the induction of settlement and metamorphosis of many marine invertebrate larvae. This transition is an absolute requirement for completion of the animal’s life cycle and is contingent on induction by exogenous morphogenetic cues, many of which are produced by bacteria associated with a particular environmental surface." http://www.pnas.org/content/110/9/3229.full View in LinkedIn

SO ENDS this consideration of the interaction of microbial entities with other creatures during development. A sea change has occurred in recent years where this is now widely acknowledged, and the story is just beginning to unfold. The interconnectedness and deep symbiotic relations between diverse phyla across vast periods of time is becoming very clear. View in LinkedIn

"AUTONOMOUS AGENTS are systems capable of autonomous, purposeful action in the real world." https://lnkd.in/dpcsNEh View in LinkedIn

OWN AGENDA. "An autonomous agent is a system situated within and a part of an environment that senses that environment and acts on it, over time, in pursuit of its own agenda and so as to effect what it senses in the future." https://lnkd.in/dpcsNEh View in LinkedIn

LEADERLESS. "An autonomous agent has a limited ability to perceive environment. An autonomous agent processes the information from its environment and calculates an action. An autonomous agent has no leader." http://natureofcode.com/book/chapter-6-autonomous-agents/ View in LinkedIn

"INTELLIGENT AGENTS continuously perform three functions: perception of dynamic conditions in the environment; action to affect conditions in the environment; and reasoning to interpret perceptions, solve problems, draw inferences, and determine actions." https://lnkd.in/dpcsNEh View in LinkedIn

MORE THAN THE SUM. "What is a complex system? A complex system is typically defined as a system that is “more than the sum of its parts.” http://natureofcode.com/book/chapter-6-autonomous-agents/ View in LinkedIn