Month: September 2022

CHURCH ON CLONING HUMANS. "Another technology that the de-extinction of a Neanderthal would require is human cloning. We can clone all kinds of mammals, so it's very likely that we could clone a human. Why shouldn't we be able to do so?" http://lnkd.in/dyPEj2H View in LinkedIn

CHURCH ON NEANDERTHAL CLONES (I). "The first thing ... is to sequence the Neanderthal genome ... been done. The next step would be to chop this genome up ... and then synthesize these. Finally, you would introduce these chunks into a human stem cell." http://lnkd.in/dZuy7g4 View in LinkedIn

NEANDERTHAL CLONES (II). "If we do that often enough, then we would generate a stem cell line that would get closer and closer to the corresponding sequence of the Neanderthal. We developed the semi-automated procedure ... Finally, we assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone." http://lnkd.in/dZuy7g4 View in LinkedIn

THE NEANDERTHAL GENOME PROJECT, "a collaborative effort between Max Planck Institute and 454 Life Sciences. A high-quality Neanderthal genome sequence: the genome sequence was generated from a toe bone discovered in Denisova Cave in southern Siberia in 2010." http://lnkd.in/dMx5dtr View in LinkedIn

ANCIENT HOMINID DNA SEQUENCED. "They sequenced the first complete nuclear genome from the hair of a 4,000-year-old Palaeo-Eskimo—the first people to settle in the New World Arctic." http://lnkd.in/dEMV2_N View in LinkedIn

NEANDERTHAL GENOME SEQUENCED. "Neandertal genome project reaches its goal. Researchers compile definitive list of the DNA sequence changes that make us human ... has determined a high-quality genome sequence of a Neandertal woman ...and is approximately 50,000-year-old." http://lnkd.in/d-VdXdp View in LinkedIn

400,000 HUMAN RELATIVE mDNA SEQUENCED. "Oldest hominin DNA sequenced, December 04, 2013: Max Planck researchers sequence the mitochondrial genome of a 400,000-year-old hominin from Spain." http://lnkd.in/d-VdXdp View in LinkedIn

MEDIA STORM OVER MISQUOTED "SEARCH FOR SURROGATE MOTHER". "An interview published last week by SPIEGEL with ... George Church has sparked frenetic media speculation about a supposed plan to bring the Neanderthal back from the dead. Church feels his remarks were misinterpreted after they were published in SPIEGEL." http://lnkd.in/drEAhjd View in LinkedIn

THE GAP. "There's a big difference between sequencing a Neanderthal genome and actually cloning one. A synthetically produced genome would need to be packaged into chromosomes that can be replicated in a cell, which we don’t know how to do yet ... MAGE, could be used to alter an induced pluripotent stem cell into the genome of a Neanderthal." http://lnkd.in/dMx5dtr View in LinkedIn

STEM CELLS, SYNBIO, MAGE, AND DE-EXTINCTION CONVERGE. "Instead of trying to build genomes from scratch, George Church ... created MAGE, a machine that harnesses the natural principles of evolution to do all the heavy lifting ... Billions of different mutant genomes can now be generated per day." http://lnkd.in/duFFnTk View in LinkedIn