Month: September 2022

NACRE AS HISTORICAL TEMPERATURE GUAGE. By analysis of the nacre on deep sea shells it is possible to reconstruct the historical temperatures of the oceans. Brilliant work. https://lnkd.in/d-BBVMX View in LinkedIn

TARGETING YOUTH by tobacco companies is both to ensure a continual base for the market, but also due to their increased biochemical susceptibility to nicotine addiction, at an age when they are already experimenting with other risky behaviors in order to differentiate themselves. A very vulnerable sector. View in LinkedIn

YOUNG BRAINS MORE SUSCEPTIBLE TO NICOTINE. "We have shown that juveniles have unique behavioral and endocrine responses to acute administration of nicotine as compared with adults. Acetaldehyde influences many but not all of these responses to nicotine." http://www.nature.com/npp/journal/v32/n9/full/1301327a.html View in LinkedIn

ADOLESCENTS ARE RIPE FOR ADDICTION. "Adolescence is a unique period in response to psychostimulants ... other constituents in tobacco and tobacco smoke may also contribute to the effects of nicotine and may, consequently, affect smoking behaviors." http://www.nature.com/npp/journal/v32/n9/full/1301327a.html View in LinkedIn

"NICOTINE ADDICTION depends on the amount of nicotine delivered and the way in which it is delivered, which can either enhance or reduce its potential for abuse: the faster the delivery, rate of absorption, and attainment of high concentrations of nicotine, the greater is the potential for addiction." Pharmacokinetics are key. https://lnkd.in/dmhcut5 View in LinkedIn

ABSOLUTE NICOTINE LEVELS ARE IRRELEVANT NOW. "The mean peak concentrations of nicotine are higher with use of tobacco products than with use of nicotine replacement products, and cigarette smoking produced both the highest peak concentration and most rapid rate of nicotine absorption." http://www.ncbi.nlm.nih.gov/books/NBK53018/ View in LinkedIn

CIGARETTE ADDITIVES BOOST THE RUSH. "The nicotine pharmacokinetics associated with cigarette smoking is likely to lead to high potential for addiction, whereas medicinal nicotine products have relatively minimal potential for addiction." Sublingual and patch nicotine kinetics to Tmax are slow, without potentiators. https://lnkd.in/dmhcut5 View in LinkedIn

MANY SMOKERS STILL IN THE DARK. "When researchers presented smokers with detailed and accurate facts about the dangers of smoking, tobacco smokers reported feelings of new motivations to quit … many smokers are still unaware of the dangers of smoking due to the successful deceitfulness of the tobacco industry." https://lnkd.in/dfqR3VW View in LinkedIn

PUBLIC UNAWARE. "Modern cigarettes have been extensively engineered and optimized as nicotine delivery devices developed through major national and international research and development programs. The average smoker has been unaware of these efforts by the tobacco industry and of the extensive manipulation of cigarette chemistry." https://lnkd.in/dazJ8n2 View in LinkedIn

"TOBACCO COMPANIES conducted a carefully crafted, decades-long campaign to manipulate throat doctors into helping to calm concerns among an increasingly worried public that smoking might be bad for their health, according to a new study ... Beginning in the 1920s, this campaign continued for over half of a century." https://lnkd.in/d3Vi8EW View in LinkedIn