21Sep 2022 by Nigel Fleming No Comments
linkedin post 2020-12-19 04:51:24

linkedin post 2020-12-19 04:51:24

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MEDICINAL USES. “Ziconotide, a pain reliever 1,000 times as powerful as morphine, was initially isolated from the venom of the magician cone snail, Conus magus. It was approved by the U.S. Food and Drug Administration in December 2004 under the name "Prialt". Other drugs are in clinical and preclinical trials, such as compounds of the toxin that may be used in the treatment of Alzheimer's disease, Parkinson's disease, depression, and epilepsy.” https://en.m.wikipedia.org/wiki/Cone_snail View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2020-12-19 04:53:00

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SHADOW OF THE MIND. “The pigmentation patterns of shells in the genus Conus can be generated by a neural-network model of the mantle. We fit model parameters to the shell pigmentation patterns of 19 living Conus species for which a well resolved phylogeny is available.” https://lnkd.in/dwfZQzE View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2020-12-19 04:55:33

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CONSTRAINTS OF COMPLEXITY. “These results are also notable because the inferred patterns of ancestral species sometimes lie outside the range of patterns of their living descendants, and illustrate how development imposes constraints on the evolution of complex phenotypes.” https://lnkd.in/dwfZQzE View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2020-12-19 04:56:29

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THE BLURR OF COMPLEXITY. “Pigmentation patterns on mollusk shells are typical complex phenotypes. They differ substantially among closely related species, but the complexity of the patterns makes it difficult to characterize their similarities and differences.” https://lnkd.in/dwfZQzE View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2020-12-19 04:58:06

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EVOLUTION OF PIGMENTATION. “In this report, we present an attempt to resolve this problem by combining phylogenetic methods with a realistic developmental model that can generate pigmentation patterns of shelled mollusks in the diverse cone snail genus Conus. https://lnkd.in/dwfZQzE View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2020-12-19 04:58:50

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THE TWO ELEMENTS. “The model is based on the interactions between pigment-secreting cells and a neuronal network whose parameters are measurable physiological quantities. The neural model used here is a generalization of models proposed earlier by Ermentrout et al. and Boettiger et al.” https://lnkd.in/dwfZQzE View in LinkedIn
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