linkedin post 2017-05-04 04:48:26

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MODIFIED DNA IN CELLS. "Guanine-rich DNA sequences that can adopt non-Watson-Crick structures in vitro are prevalent in the human genome. Whether such structures normally exist in mammalian cells has, however, been the subject of active research for decades. (We show that) Small-molecule–induced DNA damage identifies alternative DNA structures in human genes." https://lnkd.in/dj3aJwZ View in LinkedIn
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linkedin post 2017-05-04 04:42:18

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ALTERNATIVE DNA IN NATURE. "Local structural transitions from the common B-DNA conformation into other DNA forms can be functionally important. Such transitions within certain sequence elements of DNA can be induced by changes in environmental conditions, protein binding and superhelical tension. Several lines of evidence indicate that alternative DNA structures may exist in prokaryotic and eukaryotic cells. The data on their involvement in replication, gene expression, recombination and mutagenesis continues to accumulate." An excellent review. https://lnkd.in/dPQHwzR View in LinkedIn
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linkedin post 2017-05-06 05:59:43

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FRAGMENT FROM NATURE deals with culturally confined knowledge, often due to language barriers. Think: 100 years of phage antibiotic therapy in Russia; think: surgery under accupuncture for centuries; and now, think: Mugifumi, or the beneficial aspects of touch in plants. Language is not the only barrier to knowledge diffusion: scientific resistance to new ideas is perhaps more impeding. View in LinkedIn
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linkedin post 2017-05-03 04:20:43

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EXPANDED GENETIC ALPHABETS. "The possibility of increasing the number of replicable nucleotides in DNA and RNA (collectively xNA) above the standard four found in natural terran xNA was noted a quarter-century ago. However, only recently has the broader scientific community come to recognize that expanded genetic “alphabets” might also expand the functional potential of nucleic acids." https://lnkd.in/dinaF2C View in LinkedIn
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linkedin post 2017-05-07 05:45:32

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CHERRY ROOTS. "Effects of mechanical stress on trees have also been studied extensively. For instance, mechanical bending of the stem increased biomass allocation toward the root in wild cherry tree seedlings, avoiding the formation of poor root systems and the reduction of diameter growth of the trunk seen in mechanically untreated seedlings." https://lnkd.in/dDuN9mZ View in LinkedIn
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