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MENDEL THE NATURALIST. "During his childhood he worked as a gardener, and as a young man attended the Olmutz Philosophical Institute. In 1843 he entered an Augustinian monastery in Brunn, Czechoslovakia. Soon afterward, his natural interest in science and specifically hereditary science led him to start experiments with the pea plant. Mendel's attraction for scientific research was based on his love of nature in general. He was not only interested in plants, but also in meteorology and theories of evolution." https://lnkd.in/dfsvaCA View in LinkedIn

MONOGENIC INHERITANCE. "Mendelian inheritance patterns are well-established, and readily recognizable as ‘textbook’ examples, for many single gene diseases, and a few digenic cases." https://lnkd.in/d7vkJAx View in LinkedIn

GREGOR MENDEL. "There is no greater legend in the history of science than that of the experiments of Gregor Mendel. Three moments in this legend are extraordinary: first, how in the 1860s, Mendel discovered the laws governing the inheritance of individual characters; second, how the scientific world failed to recognise the monumental importance of these findings during his life-time; and third, the remarkable ‘rediscovery’ in 1900 of what later came to be called Mendelism." https://lnkd.in/dKsN9QF View in LinkedIn

SEVEN CHARACTERISTICS. "Mendel started his experiments by carefully selecting seven qualitative characters in peas (Pisum sativum L.) in 1856, and his results were published in 1866." Astonishingly this is the basis of our knowledge of predictable Mendelian inheritance. https://lnkd.in/d42Fwde View in LinkedIn

GREGOR MENDEL's work on heredity has endured 156 years, despite his Christian views and disbelief in Darwin. He was also a gentleman scientist, like many of the day, working outside traditional science funding institutions. Despite the fact that nothing was known at the time about DNA, chromosomes, genes or meiosis, his rigorous observations have largely stood the test of time. Inconsistencies of his laws have been identified and explained by modern research. View in LinkedIn

CORE. "The most important principle of Mendel's Law of Independent Assortment is that the emergence of one trait will not affect the emergence of another. For example, a pea plant's inheritance of the ability to produce purple flowers instead of white ones does not make it more likely that it would also inherit the ability to produce yellow peas in contrast to green ones." https://lnkd.in/dfsvaCA View in LinkedIn

THE EXCEPTIONS to Mendelian inheritance are perhaps as interesting as the many mechanisms that are upheld by Mendelian laws. These exceptions once again illustrate that nature is the master of innovation, and the subtlety and daring of the alternative mechanisms could barely be imagined a priori. View in LinkedIn

PART FOUR. "The fourth law states that, "The two genes for each character segregate during gamete production." This is the last part of Mendel's generalization. This references meiosis when the chromosome count is changed from the diploid number to the haploid number. The genes are sorted into separate gametes, ensuring variation." https://lnkd.in/dfsvaCA View in LinkedIn

PART THREE. "The third law, in relation to the second, declares that, "If the two alleles differ, then one, the dominant allele, is fully expressed in the organism's appearance; the other, the recessive allele, has no noticeable effect on the organism's appearance." https://lnkd.in/dfsvaCA View in LinkedIn

PART TWO. "The second law states that, "For each character trait (ie: height, color, texture etc.) an organism inherits two genes, one from each parent." This statement alludes to the fact that when somatic cells are produced from two gametes, one allele comes from the mother, one from the father. These alleles may be the same (true-breeding organisms), or different (hybrids)." https://lnkd.in/dfsvaCA View in LinkedIn