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GENETICS-FIRST CAMP "find implausible the idea that molecular networks without genetic control could have undergone Darwinian evolution." https://lnkd.in/euzMX5X View in LinkedIn

METABOLISM-FIRST CAMP. "There are two camps in the origin of life. The metabolism-first camp advocates consider improbable that RNA-like self-replicating polymers appeared before natural selection had operated on chemical networks." https://lnkd.in/euzMX5X View in LinkedIn

DEATH OR REPLICATION. "Natural selection is a mechanism by which populations adapt and evolve. In its essence, it is a simple statement about rates of reproduction and mortality: Those individual organisms who happen to be best suited to an environment survive and reproduce most successfully, producing many similarly well-adapted descendants." Impressive. https://lnkd.in/eaizZgz View in LinkedIn

SELECTIVE PROCESS. "Natural selection is the gradual, non-random process by which genetically inherited traits (alleles) become either more or less common in a population due to non-random differences in the effective reproductive rate of bearers of these genetic traits." https://lnkd.in/eS_4y_J View in LinkedIn

PREFERENTIAL SURVIVAL. "Natural selection is the differential reproduction of genotypes. ‘Natural selection […] is the differential and non-random reproduction of different alternative alleles in a population’...population genetics and modern evolutionary theory equate natural selection with differential reproduction of alternative forms of genes, genotypes, or other reproducible units’." Lovely definition. https://lnkd.in/eS_4y_J View in LinkedIn

"WHY A HIGHER MUTATION RATE occurs in the mitochondria in contrast to the nucleus appears related to the generation of genetic diversity useful in exploiting new ecological niches. In particular, the enzymes involved in energy generation by the mitochondrion. The mitochondrion is the powerhouse of the cell." https://lnkd.in/e533NK2 View in LinkedIn

"WHY A HIGHER MUTATION RATE occurs in the mitochondria in contrast to the nucleus appears related to the generation of genetic diversity useful in exploiting new ecological niches. In particular, the enzymes involved in energy generation by the mitochondrion. The mitochondrion is the powerhouse of the cell." https://lnkd.in/e533NK2 View in LinkedIn

MITOCHONDRIAL INHERITANCE. The maternal inheritance of mitochondrial DNA, a primer. https://lnkd.in/eUuXV43 View in LinkedIn

HOMOPLASTY VS HETROPLASTY. “A mammalian cell has a single nucleus which contains a single genome. The genomic DNA is identical across all cells in an organism. A mammalian cell has many mitochondria and every mitochondria has its own (circular) genome. All the many individual copies of mtDNA exist independently of each other. If all the mtDNA in a cell are identical, then they are homoplasmic. (Common, "normal" situation). If one (or more) of the mtDNA in a single cell acquires a mutation, then the cell will have a mix of mutant-mtDNA and WT-mtDNA. These cells are now heteroplasmic.” https://lnkd.in/eeWUxj8 View in LinkedIn

"EXTRANUCLEAR INHERITANCE or cytoplasmic inheritance is the transmission of genes that occur outside the nucleus. It is found in most eukaryotes and is commonly known to occur in cytoplasmic organelles such as mitochondria and chloroplasts or from cellular parasites like viruses or bacteria." This breaks all of Mendel’s famous genetic laws. https://lnkd.in/eWiwdUk View in LinkedIn