linkedin post 2018-04-08 05:11:48

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TOWARDS MULTIPLE-CODING. “The generation of a given superstructure through self-organization results, in its simplest form, from the operation of a single-code assembly program. A step beyond consists in devising systems of higher complexity that operate in multimode fashion through the implementation of several codes within the same overall program, resulting in multiple self-organization processes.” https://lnkd.in/dN969hA View in LinkedIn
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linkedin post 2018-04-08 05:09:46

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LIQUID CRYSTAL ASSEMBLY. ““Discotic liquid crystals form by the assembly of “sector”-shaped components into disks, which thereafter organize into columns, and template binding by molecular strands induces wrapping into helical disk-like objects, which then aggregate into large supramolecular assemblies.” https://lnkd.in/dN969hA View in LinkedIn
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linkedin post 2018-04-08 05:06:42

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KINETICS AND THERMODYNAMICS. “Because it is a time-dependent process, self-organization also involves temporal information and may display kinetic control, generating kinetic products before reaching the thermodynamic one(s). This is the case in the initial assembly of a triple helical complex that evolves toward a circular helicate.” https://lnkd.in/dN969hA View in LinkedIn
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linkedin post 2018-04-08 05:04:49

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TOWARDS INSTRUCTED COMPLEXITY. “The implementation of this instructed mixture paradigm is crucial for the development of complex chemical systems, as witnessed by the build-up of organized species and the execution of highly integrated functions that take place side-by-side in the assembly and operation of the machinery of the living cell.” https://lnkd.in/dN969hA View in LinkedIn
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linkedin post 2018-04-09 02:59:05

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GENOMICS AND HOLISM. “The tremendous growth of interest in systems biology was driven by the simultaneous rise of genomics, which is the field dedicated to the large-scale analysis of the properties of genomes.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn
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linkedin post 2018-04-08 05:02:30

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INSTRUCTED MIXTURES. “Rather than pursuing mere chemical purity of a compound or a material, one seeks to design instructed components, which, as mixtures, allow the controlled assembly of multiple well-defined supramolecular species, following specific programs and interactional algorithms.” https://lnkd.in/dN969hA View in LinkedIn
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linkedin post 2018-04-10 03:48:26

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EXTREME NODE. “The combinatorial nature of gene regulation points to another extreme, where we are interested in identifying relatively small cohorts of genomic regions that show similar coordinated changes of chromatin marks and transcription factor binding across many data sets and multiple cell types.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn
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