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LIKELY TIP OF ICEBERG. "We suspect that systematic surveys of phage genomes in intimate host-associated bacteria may uncover a broad range of eukaryotic-like protein domains involved in phage life cycle adaptations and phage–eukaryote interactions." https://lnkd.in/dYh3-r4 View in LinkedIn

LIBERAL GENE TRANSFERS. "Bacteriophage WO frequently transfer between Wolbachia co-infections in the same animal host and to the host genome as part of large transfers of the Wolbachia chromosome." https://lnkd.in/dYh3-r4 View in LinkedIn

KEY FUNCTIONS. "In phage WO, these animal protein domains are central to anti-eukaryotic functions including the black widow latrotoxin, PCD (NACHT), immune evasion (PRANC) and protein–protein interactions." https://lnkd.in/dYh3-r4 View in LinkedIn

MIRROR. "The presence of eukaryotic-like protein domains in bacteriophage genomes is of special note as they curiously mirror eukaryotic genes in large eukaryotic viruses that aid in viral mimicry and manipulation of host processes." https://lnkd.in/dYh3-r4 View in LinkedIn

Ben Jennings on Brett Kavanaugh's confirmation to the supreme court – cartoon https://www.theguardian.com/commentisfree/picture/2018/oct/07/ben-jennings-on-brett-kavanaughs-confirmation-to-the-supreme-court-cartoon?CMP=Share_iOSApp_Other View in LinkedIn

LATERAL MOVE. "To the best of our knowledge, these eukaryotic-like domains have never before been reported in packaged bacteriophages and their phylogeny, distribution and sequence diversity imply lateral transfers between bacteriophage/prophage and animal genomes." https://lnkd.in/dYh3-r4 View in LinkedIn

EVOLUTION OF DEATH FROM IMMORTALITY. "The above results thus support our hypothesis that originally immortal organisms evolve into mortal organisms by acquiring a new genetic program for autonomous death." http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.657.723&rep=rep1&type=pdf View in LinkedIn

HIJACKED GENES. "We suggest that the evolution of these eukaryotic protein domains in bacteriophage WO parallels the evolution of eukaryotic genes in canonical eukaryotic viruses, namely those commandeered for viral life cycle adaptations." Curiously, skipping strict domains. https://lnkd.in/dYh3-r4 View in LinkedIn

SLOWLY DOMINANT MUTANT MORTALS. "Our findings suggest that a mortal organism, born among a population of immortal organisms, cannot reproduce and becomes extinct in many cases. Nonetheless, a number of mortal organisms did manage to survive at a small but significant rate. Moreover, once a mortal organism survives, it extends its habitation area, surpasses immortal organisms and prospers without exception." http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.657.723&rep=rep1&type=pdf View in LinkedIn

ANIMAL TO PHAGE. "These various protein domain families are central to eukaryotic functions and have never before been reported in packaged bacteriophages, and their phylogeny, distribution and sequence diversity implies lateral transfer from animal to bacteriophage genomes." https://lnkd.in/dYh3-r4 View in LinkedIn