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BUILDING NEW LIFE FORMS. "Synthetic biology as the next disruptive platform. Today, the tools of synthetic biology enable the application of mathematical and engineering principles to biological systems. This allows researchers to design, build and test new genomes much more quickly." http://www.prescouter.com/2015/07/synthetic-biology-the-next-big-disruptor/ View in LinkedIn

FEMALE MATING BEHAVIOR. “SFPs influence female behaviour or physiology in a way that makes her less likely to mate again. This is advantageous to the male, but may be disadvantageous to the female – females in insects usually experience a net benefit from multiple mating.” (SFPs = male seminal fluid proteins). http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

INFLUENCES ON PATERNITY. “Some of the female response to mating may exist to influence the outcome of this competition via cryptic female choice, but males would be selected to overcome this. Consistent with this notion, paternity is known to be affected by both male and female genotype, often in a nonadditive way.” http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

SEXUAL CONFLICT. “The female reproductive tract also acts as an arena for sexual conflict – the optimal outcome of sexual interactions is likely to differ between males and females. First, sperm and SFPs have presumably been selected to increase the male's success in direct sperm competition with the sperm of other males within the female reproductive tract. This function of SFPs is supported by the fact that males transfer more SFPs during mating if another male is present, implying a greater risk of sperm competition.” (SFPs = male seminal fluid proteins). http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

FEMALE SPERM STORAGE. “Some of this transition to storing sperm is regulated by interactions between SFPs and innervated stretches of the reproductive tract. Later, in order for fertilization to occur, both female secretions and male SFPs are required. Perhaps the most compelling evidence of synergy comes from recent studies demonstrating a stepwise seminal fluid proteolytic cascade with diverse effects on reproductive processes that requires both male and female contributions.” (SFPs = male seminal fluid proteins). http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

FEMALE FLY SWITCH. “On the surface, sexual molecular interactions in Drosophila often appear to function cooperatively. For example, the switch to a reproductive state involves female processing of male-derived molecules that trigger ovulation. SFPs, but not sperm, are also necessary for conformational changes in female anatomy that allow sperm to enter storage.” (SFPs = male seminal fluid proteins). http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

TRIGGER OF FEMALE RESPONSE. “Many of these changes are mediated by male seminal fluid proteins (SFPs). It remains an open question to what extent these changes reflect synergy between male and female molecules generating a female's post-mating transition to a reproductive state versus antagonistic interactions fuelled by sexual conflict.” http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

FLY FEMALE MATING RESPONSE. “This is accompanied by a suite of phenotypic changes, including an immune response, altered feeding behaviour and sleep and activity patterns, and reduced sexual receptivity.” http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

FRUIT FLY POST COITUS. “Females respond to mating in diverse ways that include physiological, anatomical and behavioural changes. In Drosophila melanogaster, the well-characterized female post-mating response involves changes in expression levels of thousands of genes in both the reproductive tract and elsewhere in the soma, with a strong temporal pattern.” http://onlinelibrary.wiley.com/doi/10.1111/jeb.12763/full View in LinkedIn

EJACULATE TRIGGER. “In many species with internal fertilization, molecules transferred in the male ejaculate trigger and interact with physiological changes in females. It is controversial to what extent these interactions between the sexes act synergistically to mediate the female switch to a reproductive state or instead reflect sexual antagonism evolved as a by product of sexual selection on males.” https://lnkd.in/e4e-PaN View in LinkedIn