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"SELF-REPLICATION occurs when an informational molecule (such as a nucleic acid) directs the spontaneous synthesis of a replica of itself. Mechanisms for self-replication can be autocatalytic, where a molecule acts as a template to make a direct copy of itself, or cross-catalytic, where two or more molecules of different informational content amplify one another." http://link.springer.com/referenceworkentry/10.1007%2F978-3-642-11274-4_1423 View in LinkedIn

THE BIG GAP. "While the last century brought an exquisite understanding of the molecular basis of life, very little is known about the detailed chemical mechanisms that afforded the emergence of life on early earth." https://lnkd.in/dWndif7 View in LinkedIn

EMERGENT PROPERTIES. "These properties are sometimes referred to as “emergent” properties because they emerge from the whole and are not properties of the individual parts." https://scholar.google.es/scholar?q=in+silico+chemistry+of+emergence+of+life&hl=en&as_sdt=0&as_vis=1&oi=scholart&sa=X&ved=0ahUKEwj40qHQlMXLAhWCnRoKHRtCAjkQgQMICDAA View in LinkedIn

INTEGRATIVE APPROACHES. "It has become generally accepted that the integrative analysis of the function of multiple gene products has become a critical issue for the future development of biology. It is thus likely that over the coming years and decades, the biological sciences will be increasingly focused on the systems properties of cellular and tissue functions. These are the properties that arise from the whole, and represent “real” biological properties." https://scholar.google.es/scholar?q=in+silico+chemistry+of+emergence+of+life&hl=en&as_sdt=0&as_vis=1&oi=scholart&sa=X&ved=0ahUKEwj40qHQlMXLAhWCnRoKHRtCAjkQgQMICDAA View in LinkedIn

REDUCTIONISM. "During the latter half of the 20th century, biology was dominated by reductionist approaches that successfully generated information about individual cellular components and their functions. Over the past decade, this process has been greatly accelerated by the emergence of genomics." https://scholar.google.es/scholar?q=in+silico+chemistry+of+emergence+of+life&hl=en&as_sdt=0&as_vis=1&oi=scholart&sa=X&ved=0ahUKEwj40qHQlMXLAhWCnRoKHRtCAjkQgQMICDAA View in LinkedIn

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THE SECRET OF LIFE'S ORIGIN has been evasive. In part because it had eons in which to happen, under conditions we could hardly begin to replicate. Included in this question is the simple, yet heretical, question — did life only arise on Planet Earth? View in LinkedIn

Great initiative! https://www.theguardian.com/world/2018/dec/05/luxembourg-to-become-first-country-to-make-all-public-transport-free?CMP=Share_iOSApp_Other View in LinkedIn

LIFE ORIGINS. "According to their model, during the night cycles, multiple short polymers bond to longer polymer strands, which act as templates. These longer template strands hold the shorter polymers in close enough proximity to each other that they can ligate to form a longer strand -- a complementary copy of at least part of the template. Over time, the newly synthesized polymers come to dominate, giving rise to an autocatalytic and self-sustaining system of molecules large enough to potentially encode blueprints for life, the model predicts." https://publishing.aip.org/publishing/journal-highlights/origins-life-new-model-may-explain-emergence-self-replication-early View in LinkedIn

REPLICON PROOF. "My colleagues and I... have designed such self-assembling molecules and crafted them in the laboratory... Our organic molecules, although they operate outside of living systems, help to elucidate some of the essential principles of self-replication.'' https://lnkd.in/dn83zJW View in LinkedIn