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OUT OF THE BOX. "We are bound to face those risks whether or not we seek to harness the full power of the Net, since the teeming and inevitable population of uncaged digital organisms will in any case plow forward with its own relentless exploration of the Net's capabilities." https://lnkd.in/edrARjk View in LinkedIn

PRIMORDIAL NET. "This coming Net of distributed resources will be tremendously powerful, and tremendously hard to harness because of its decentralized nature. It will be an ecology of computing machines, and managing it will require an ecological approach." https://lnkd.in/e6ExXVY View in LinkedIn

OUT OF THE BOX. "We are bound to face those risks whether or not we seek to harness the full power of the Net, since the teeming and inevitable population of uncaged digital organisms will in any case plow forward with its own relentless exploration of the Net's capabilities." https://lnkd.in/edrARjk View in LinkedIn

UNIMAGINABLE. "Trying to imagine the marvels that pour forth once you've successfully tapped a computer as elaborate as the Net is as futile as trying to map the future of a society, or of a life – or of life itself." https://lnkd.in/edrARjk View in LinkedIn

"A WATERSHED in the history of computing. It has long been observed, rather wistfully, that in principle the world's computers sum up to one gigantic parallel processor, and that the crushing bulk of that metacomputer's CPU cycles goes to waste, unused. Only now, however, with the advent of protocols like Telescript and Tierra, do we have the means to deploy such processes that treat the Net as one machine, safely and sensibly." https://lnkd.in/edrARjk View in LinkedIn

PRESENT IN METAZOANS? “Considering that the various building blocks are highly conserved throughout the animal kingdom, it appears possible that similar strategies to create complex modular structures through combinatorial assembly of primary metabolites are not only prevalent among nematodes, but present in metazoans in general.” https://lnkd.in/d4DhYhz View in LinkedIn

LEGO SETS. “Our ongoing research also revealed that nematodes produce a large diversity of additional compounds by the combinatorial assembly of building blocks from primary and secondary metabolic pathways.” https://lnkd.in/d4DhYhz View in LinkedIn

WORD ORGANIZATION. “Ascarosides are organized in a very similar fashion, because they are all based on the dideoxy-sugar ascarylose and feature variations in the attached fatty-acid-derived side chain. Analogous to bacterial AHL signaling, different nematode species produce and respond to specific combinations of ascarosides. Based on recent findings describing modular assembly of ascaroside structures from a diverse array of biosynthetic building blocks, it is likely that many additional ascaroside structures exist in nematodes, perhaps also in species we analyzed in this study.” https://lnkd.in/d6G6mZ9 View in LinkedIn

BACTERIAL ANALOGY. “The conserved nature of ascaroside signaling is evocative of bacterial quorum sensing, where acyl homoserine lactones (AHLs) are both produced and sensed by many species of gram-negative bacteria. AHLs are based on a small invariable core structure, the homoserine lactone, which bears a fatty-acid-derived side chain featuring species-specific chemical modifications.” https://lnkd.in/d6G6mZ9 View in LinkedIn

DISTRIBUTION UNCERTAIN. “Ascarosides have not yet been found in any other animal phylum, and thus we hypothesized that short-chain ascarosides comprise a nematode-specific chemical code mediating a variety of behaviors in many different species.” https://lnkd.in/d6G6mZ9 View in LinkedIn