Category: Uncategorized

FINE LINE COOPERATION. "Computers can't have a back-room conversation to fix prices, but they can predict the way that other computers are going to behave. And with that information, they can effectively cooperate with each other in advancing their own profit-maximizing interests." http://www.businessinsider.com/robots-colluding-to-manipulate-markets-2015-4 View in LinkedIn

CIRCADIAN LINKS. "PACAP has also been shown to directly influence clock gene expression and affect signalling pathways that integrate the molecular clock in the functionality of circadian rhythms in a dose- and phase-dependent manner." http://rspb.royalsocietypublishing.org/content/early/2011/02/11/rspb.2010.2567 View in LinkedIn

BEHAVIORAL AND PHYSIOLOGIC LINKS. "PACAP has a broad spectrum of biological functions with profound influence on physiology and behaviour. Most of the reported effects exerted by PACAP are indeed strongly linked to the physiological and behavioural shifts described for avian migration." http://rspb.royalsocietypublishing.org/content/early/2011/02/11/rspb.2010.2567 View in LinkedIn

NEUROPEPTIDE CANDIDATE. "The ADCYAP1 gene encodes the pituitary adenylate cyclase-activating polypeptide (PACAP), which is one of the most studied neuropeptides (more than 3000 papers deal directly with PACAP). The peptide and its receptors are widely distributed in the brain and in various peripheral organs." http://rspb.royalsocietypublishing.org/content/early/2011/02/11/rspb.2010.2567 View in LinkedIn

MIGRATORY GENE CANDIDATE. "We found a consistent association between a microsatellite polymorphism and migratory behaviour only at one candidate locus: the ADCYAP1 gene. This polymorphism explained about 2.6 per cent of the variation in migratory tendency among populations, and 2.7–3.5% of variation in migratory restlessness among individuals within two independent populations." http://rspb.royalsocietypublishing.org/content/early/2011/02/11/rspb.2010.2567 View in LinkedIn

KAPUT (CLOCK) mRNA. "Phase relationship in mRNA oscillations was altered between oscillator components in the circadian pacemaker system (retina, pineal, hypothalamus) as well as in the peripheral (liver, muscle) tissues. These results show for the first time altered waveforms of clock gene expressions in all tissues in parallel with behavioral shifts and suggest the involvement of circadian system in photoperiod induction of seasonal LHSs in a migratory species." (LHS = life history states). http://www.fasebj.org/content/29/10/4248.full View in LinkedIn

HYPOTHESIS. "It remains largely unknown how the circadian clock connects to photoperiod-induced seasonal change in physiology and behavior in vertebrates. We hypothesized phase and amplitude plasticity in the oscillations of Per2, Cry1, Bmal1, and Clock genes with photoperiod-induced phenotypes in a seasonal species." http://www.fasebj.org/content/29/10/4248.full View in LinkedIn

"CLOCK POLYMORPHISM has been found to be associated with breeding in the blue tit (Cyanistes caeruleu) and migratory barn swallows (Hirundo rustica). Similarly, midday and midnight Ror-α and Rev-erb-α mRNA expressions have been found to vary with photoperiod-induced phenotypes in the night-migratory black-headed bunting (Emberiza melanocephala)." http://www.fasebj.org/content/29/10/4248.full View in LinkedIn

CIRCADIAN CONTROL. "Circadian pacemaker in the suprachiasmatic nuclei shows phase plasticity with winter and summer photoperiod in seasonal mammals. In vertebrates, the circadian molecular oscillator is based on transcriptional-translational feedback loops, in which periods and cryptochromes are negative regulators of their own transcription driven by brain and muscle arnt-like protein 1 (Bmal1) and circadian locomotor output cycles kaput (Clock) transcriptional activators." http://www.fasebj.org/content/29/10/4248.full View in LinkedIn

LIGHT IMPACT. "When continuously exposed to long days, short day photosensitive migratory birds show successive seasonal life-history states, characterized by premigratory (initiation of lipogenesis and gametogenesis), migratory (fat deposition and increased body mass, recrudesced gonads, and nocturnal migratory restlessness, known as Zugunruhe, and postmigratory [fat stores depleted and lean body mass, regressed gonads, return to day activity, and development of photorefractoriness; long day refractory)] phenotypes." http://www.fasebj.org/content/29/10/4248.full View in LinkedIn