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NO GEEVES. “Some people think an advanced AI will be some kind of super-butler, doing whatever they ask with incredible efficiency. But it’s more accurate to imagine an Outcome Pump: a non-sentient device that makes some outcomes more probable and other outcomes less probable. (The Outcome Pump isn’t magic, though. If you ask it for an outcome that is too improbable, it will break).” https://lnkd.in/dmZgBnF View in LinkedIn

UNDERSTATEMENT. “Machine intelligence would be a development of almost unprecedented impact and risk, well worth considering now.” http://intelligence.org/files/AIFoomDebate.pdf View in LinkedIn

THE FUSION. “As the human era comes to a close, the fate of biological (post)humanity is more likely to be symbiosis with AI followed by metamorphosis, not simple replacement.” http://www.biointelligence-explosion.com/ View in LinkedIn

NO LOOKING BACK. “Whereas genetic change in biological humanity has always been slow, the software run on serial, programmable digital computers is executed exponentially faster (cf. Moore's Law); it's copyable without limit; it runs on multiple substrates; and it can be cheaply and rapidly edited, tested and debugged.” http://www.biointelligence-explosion.com/ View in LinkedIn

WILLFUL MUTANTS. “The ability genetically to hack one's own source code will unleash an exponential growth of genomic rewrites - not mere genetic tinkering but a comprehensive redesign of "human nature".” http://www.biointelligence-explosion.com/ View in LinkedIn

REPLICATION. “Viruses are genetic material encased in protein. They self-replicate and cause disease. Prions are just proteins. They self-replicate and cause disease. How viruses and prions work. Self-replication by hijacking or inducing mis-folding, respectively, might not be what biologists have in mind for self-replication, but the end result is still more virus particles and prions in the world.” https://lnkd.in/dzZgRcM View in LinkedIn

FUTURIST VISION. "As the era of open-source genetics unfolds, tomorrow's biohackers will add, delete, edit and customise their own legacy code in a positive feedback loop of cognitive enhancement.” http://www.biointelligence-explosion.com/ View in LinkedIn

PRIONS “can multiply exponentially and can pass through membranes; transmission can occur between individual (e.g. by blood); they can even be transmitted between different species; they are resistant against proteases (enzymes that break down proteins) and the body’s defense mechanisms; they can mutate, creating different forms of pathogenic prions.” https://lnkd.in/dN2v7fv View in LinkedIn

THE CYCLE. “The accelerating growth of germline engineering will be a comparatively slow process. In this scenario, sentient biological machines will design cognitively self-amplifying biological machines who will design cognitively self-amplifying biological machines.” http://www.biointelligence-explosion.com/ View in LinkedIn

ORIGINS. “During the emergence of metazoa, a cysteine-flanked core domain was inserted, or de novo arose, in a pre-existing ZIP ancestor gene to generate a prion-like ectodomain in a sub-branch of ZIP genes. Approximately a half-billion years later, a genomic insertion of a spliced transcript coding for such a prion-like ZIP ectodomain may have created the prion founder gene.” https://lnkd.in/d9yFgCg View in LinkedIn