linkedin post 2020-01-26 05:08:00

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NON-LINEAR. “The absolute number of neurons in the rodent and primate cerebral cortex does increase much faster in larger brains compared to the number of neurons in the combined brainstem, diencephalon and basal ganglia, and is accompanied by a similarly fast increase in the number of neurons in the cerebellum.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-26 05:06:14

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FOOTNOTE. “It should be noted that the unchanging proportional number of neurons in the cerebral cortex relative to the whole brain does not contradict an expansion in volume, function and number of neurons of the cerebral cortex in evolution.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:54:40

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A LEVELING FACT. “Remarkably, the human cerebral cortex, which represents 82% of brain mass, holds only 19% of all neurons in the human brain – a fraction that is similar to the fraction that we observed in several other primates, rodents, and even insectivores.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:52:40

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RED HERRING. “Although not observed in the comparatively small rodent species analyzed, the enlargement of the cerebral cortex is not, in principle, an exclusive feature of the human brain: a similar expansion of the mass of the cerebral cortex, relative to the whole brain, is predicted by both the rodent and primate cellular scaling rules, irrespective of the number of neurons contained in the cortex.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:48:38

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AMPLIFIED SCALING FAILS. “A generic rodent brain of human-sized proportions, weighing 1.5 kg: such a brain would have only 12 billion neurons, and a much larger number of 46 billion non-neuronal cells. This number of neurons is smaller than the number of neurons estimated to exist in the human cerebral cortex alone, and about seven times smaller than the number of neurons predicted for a 1.5-kg brain built with the scaling rules that apply to primates.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:47:30

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AMPLIFYING THE LINE. “The significance of the difference in scaling rules for building brains with large numbers of neurons becomes even more obvious if one considers the expected number of neurons for a generic rodent brain of human-sized proportions.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:46:28

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MORE NUMBERS. “Likewise, the capuchin monkey brain has more than twice the number of neurons of the larger-brained capybara (3.7 billion against 1.6 billion), and also about four times more neurons in the cerebral cortex (1.1 billion against 0.3).” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:45:22

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THE NUMBERS. “With 1468 million neurons, owl monkeys have almost twice as many neurons in the brain as agoutis (which hold 857 million), and about four times more neurons in the cerebral cortex than the agouti (442 million versus 113 million).” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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linkedin post 2020-01-25 04:44:23

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SEEKING CORRELATION. “Now that absolute numbers of neurons can be compared across the similar-sized brains of agoutis and owl monkeys, and of capybaras and capuchin monkeys the expected correlation between cognitive ability and numbers of neurons is actually found to hold.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/ View in LinkedIn
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