THE FINDING. “Bekenstein conjectured the existence of a universal upper bound...on the entropy content of physical systems with negligible self-gravity.” https://lnkd.in/d3sfhP6 View in LinkedIn
HYPOTHETICAL FUNCTION. “Left-handed double helical DNA regions might be anticipated to facilitate replication fork movement and chain separation during DNA replication.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
One assumes that slate is a dull material, but the work Alberto Martinyez of Zaragoza Spain shows otherwise. He happens to be one of Spain’s leading stone caligraphers. View in LinkedIn
DARK MATTER. “Now, scientists have created the largest ever map of this mysterious substance – and it could imply that there’s something wrong with Einstein’s theory of relativity. They have also mapped the location of vast cosmic voids where the conventional laws of physics may not apply.” Read the last sentence again. https://lnkd.in/dPsJYV3 View in LinkedIn
LEVOROTATORY VARIANT. “Although there was discussion of the possibility of left-handed helices, especially shortly after the double helix formulation, there were very few systematic studies of left-handed helices published during the next decade or so.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
THE VARIANTS. “The greater wealth of diffraction data seen in the A pattern made it possible to get more information. The relative ease with which it slipped into the B pattern reinforced the idea that these were two conformational variants; it was found that both patterns could be fitted by a right-handed double helix.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
METHODOLOGICAL LIMITATIONS. “Considerable attention was paid to the fact that under certain conditions alternative conformational variants were seen. The most important of these was the A-DNA pattern which originally was produced by air-dried fibers.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
THE MANTRA. “One assumption was that the structure was perfectly regular with an asymmetric unit consisting of one nucleotide. However, the agreement was reasonable and this led to the general adoption of the right-handed B-DNA conformation as the predominant form in biological systems.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
THE PROBLEM. “The X-ray diffraction patterns were limited, and far from atomic resolution. Because of the limited resolution the patterns had to be interpreted and a number of assumptions made.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
SLOPPY DATA. “It was obvious to workers in the field, however, that although DNA fiber analysis generated physical data in agreement with the Watson-Crick structure, they did not unambiguously prove the structure.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn