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"CELL WALL-DEFICIENT variants of bacteria that normally possess a wall have been described many times in the literature, since the original report of Klieneberger nearly 80 years ago ... the new L-form cells completely abandon the normally essential cell division machinery used by virtually all extant bacterial cells, and proliferate instead by a mechanism of membrane tubulation or blebbing." https://lnkd.in/dKmZZzy View in LinkedIn

DNA ORIGAMI FOR DRUG DELIVERY. "DNA origami hinged barrel with logic gates for programmable delivery of drugs. The DNA barrel, which acts as a container, is held shut by special DNA latches that can recognize and seek out combinations of cell-surface proteins, including disease markers. When the latches find their targets they reconfigure, causing the two halves of the barrel to swing open and expose its payload." https://lnkd.in/d6RPeMH View in LinkedIn

CELL WALL DRIVERS. "The shapes of bacteria are determined by their cell walls, and with no cell wall, the L-forms have different shapes from their parent cells. For example, the L-forms of rod-shaped bacteria are typically spherical. L-forms also lack the internal cytoskeleton and cell organelles of their parent cells, creating novel morphological units including filaments, vesicles and granules." https://lnkd.in/dTCkxDw View in LinkedIn

DNA PROGRAMMABLE MOLECULES. "To assemble into specific configurations using the same chemical principles that bind the double helix of the genome. In this way, scientists have woven strands of DNA into complex nanoscale shapes: boxes with switchable lids, letters of the alphabet, even tiny world maps." https://lnkd.in/dzmMmjE View in LinkedIn

THE MARSHALL HYPOTHESIS, as we will see, is an interesting conjecture by an unqualified person that has gone beyond an interesting conjecture to become an unsubstantiated medical protocol. Left as simply a conjecture, it remains provocative, and denies Koch's famous postulates. View in LinkedIn

SPACE EXPLORATION. "One application that highlights the advantages of self-reconfigurable systems is long-term space missions. These require long-term self-sustaining robotic ecology that can handle unforeseen situations and may require self repair. Self-reconfigurable systems have the ability to handle tasks that are not known a prioritise especially compared to fixed configuration systems." http://en.m.wikipedia.org/wiki/Self-Reconfiguring_Modular_Robotics View in LinkedIn

FRAGMENT FROM NATURE this weekend is on bacteria without cell walls represent a peculiar class of organisms. They are called L-Form bacteria, and are a natural experiment for life without cells walls, as well as a model for an early primitive life form. These creatures turn out to be particularly interesting. This dovetails with the membrane adaptations of extremophile bacteria in previous Fragments. View in LinkedIn

FUTURE OF DNA BOTS. "Eventually, such DNA bots might be given the ability to replicate and evolve, at which point this variety of programmable matter could become increasingly complex and capable on its own." https://lnkd.in/dzmMmjE View in LinkedIn

EVOLVING MOLECULAR BOTS. "Nanotechnologists ... see the future of intelligent machines at the level of molecules: tiny robots that evolve and ... come together to form intelligent superorganisms. Perhaps the future of artificial intelligence will be both silicon- and carbon-based: digital brains directing complex molecular structures to copulate at the nanometre level and reproduce." Robotic swarming superorganisms. https://lnkd.in/dhAg_hD View in LinkedIn

FUTURE SPACE AMBASSADORS. "The goal ... is for future robots to be self-learning and self-replicating, armed with a 3D printer that would allow automatons to create new robots or tools to solve problems, like navigating an asteroid." https://lnkd.in/dPJh5nY View in LinkedIn