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VARIOUS STIMULI. "A truly polymodal ion channel, TRPA1 is activated by various stimuli, including electrophilic chemicals, oxygen, temperature, and mechanical force, yet the molecular mechanism of TRPA1 gating remains obscure." https://lnkd.in/erPHnzY View in LinkedIn

TRP FAMILY. "Several dozen TRP channels have been identified and are classified into six subfamilies, including the TRP ankyrin family (TRPA), with varying degrees of sequence similarity and permeability to cations. TRPA1 is the only member of the ankyrin subfamily so far identified in mammals, and it contains at least 14 ankyrin repeats in the N-terminal intracellular domain." https://lnkd.in/ecaVp5Q View in LinkedIn

STRUCTURAL RELATIVES. "Transient receptor potential (TRP) channels are diverse six-transmembrane domain (6-TM) cation channels that are related to, and share, the transmembrane topology and functional domain structure of the tetrameric voltage-gated ion channels." https://lnkd.in/ecaVp5Q View in LinkedIn

SEEING THROUGH WALLS. "We propose to use transformation optics to generate a general illusion such that an arbitrary object appears to be like some other object of our choice." https://lnkd.in/eyBstN6 View in LinkedIn

SUPERFAMILY. "These channels are classified into subfamilies, namely canonical (TRPC), melastatin (TRPM), ankyrin (TRPA), and vanilloid (TRPV). Some of these channels are activated by heat (TRPM2/4/5, TRPV1-4), while others by cold (TRPA1, TRPC5, and TRPM8)." https://lnkd.in/eZQCjnY View in LinkedIn

PEEP HOLE. "The researchers have even found a mind-boggling application. Their idea is to create the illusion that a wall has a hole in it, and then use the hole to look through the wall. That’s not quite as bonkers as it sounds. The wall has to be pretty thin, and what the new device does is allow light to tunnel through the wall in a way that would not ordinarily be possible. Amazing, if it works." https://lnkd.in/exKwCuQ View in LinkedIn

SUPERFAMILY. "A class of ion channels that belongs to the transient receptor potential (TRP) superfamily and is present in specialized neurons that project to the skin has evolved as temperature detectors." https://lnkd.in/eZQCjnY View in LinkedIn

STEP TWO. "The second step is to then distort this plane wave in the way that an elephant would. This means creating transformational material that distorts a plane lightwave in the same way as an elephant. So anybody looking at this mouse would instead see an elephant." https://lnkd.in/exKwCuQ View in LinkedIn

TRPA1 SUPERFAMILY. "TRPV1 and TRPV2 are activated by heat in the noxious range (>42°C and >52°C, respectively), whereas TRPA1 is reported to be activated by noxious cold (

STEP ONE. "So a plane wave would be bent by the mouse but then bent back into a plane as it passes through the complementary material, making the mouse disappear." https://lnkd.in/exKwCuQ View in LinkedIn